Medindia » Medication Manual » Prasugrel

Prasugrel

Updated on : November - 2012
Latest prescription information about Prasugrel. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Email Email print Print Save this page Save Syndicate Syndicate
Generic Name : Prasugrel
Pronunciation : PRA-soo-grel
Therapeutic Classification : Platelet Aggregation Inhibitor
ICD Code : Y44.4
Trade Name(s): 
India- Pasugen, Prasudoc, Prasulet, Prasurel, Prasusafe.
International- Effient.
Why it is prescribed (Indications) : 
This medication is a platelet aggregation inhibitor, prescribed for thrombotic cardiovascular (CV) events (life-threatening problems with the heart and blood vessels), in patients who had heart disease or undergone angioplasty.  It slows or stops platelets from clumping together to form clots.
When it is not to be taken (Contraindications): Contraindicated in patients with active pathological bleeding, stroke, and hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : 
Adult- PO- The recommended dose is 60mg as a single dose.
How it should be taken : 
It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of heart attack, stomach or intestinal problems, recent injury, bleeding disorder, sugar, liver problems, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* It may reduce platelet counts; avoid injury or bruising.
* It may cause dizziness; do not drive a car or operate machinery while taking this medication.
* Avoid abrupt withdrawal.
* Patient may develop with increased risk of serious and life-threatening condition called thrombotic thrombocytopenic purpura (TTP) with the following symptoms: patches on the skin, fever, weakness, unusually pale skin, yellowing of the skin or eyes. If it is so consult with your doctor.
* Monitor blood pressure regularly while taking this medication.
Side Effects : 
Bleeding disorders - Nose bleed, gastrointestinal bleeding, blood vomiting, bruising, post-procedural bleeding, accumulation of fluid in heart, and retinal bleeding.
Severe effects - Abnormal decrease in platelets, anemia, abnormal liver function, allergic reactions and shock.
Heart - High or low blood pressure, abnormal heart rhythm, chest pain, swelling in the heart muscles and slow heart rate.
Central Nervous System - Headache, fatigue and dizziness.
Metabolic - Increase in blood cholesterol.
Miscellaneous - Back pain, difficulty in breathing, nausea, vomiting, cough, rash, fever, swelling in the extremities, and diarrhea.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature (20 to 25°C), and in an airtight container.

Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.

Browse the Drugs alphabetically

Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
Drugs Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z