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Prasugrel - Indications, Dosage, Side Effects and Precautions

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Information about Prasugrel

Generic Name : Prasugrel
Up-to-date prescription details regarding Prasugrel are provided here.

Pronunciation : PRA-soo-grel

Learn the correct pronunciation of the Prasugrel, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y44.4 Therapeutic Classification : Platelet Aggregation Inhibitor

Trade Names/Brand Names of Prasugrel

India :

International :


Effient

Why is Prasugrel Prescribed? (Indications)

This medication is a platelet aggregation inhibitor, prescribed for thrombotic cardiovascular (CV) events (life-threatening problems with the heart and blood vessels), in patients who had heart disease or undergone angioplasty.  It slows or stops platelets from clumping together to form clots.

When should Prasugrel not be taken? (Contraindications)

Contraindicated in patients with active pathological bleeding, stroke, and hypersensitivity.

What is the dosage of Prasugrel?

Adult- PO- The recommended dose is 60mg as a single dose.

How should Prasugrel be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Prasugrel?

• Caution should be exercised in patients with history of heart attack, stomach or intestinal problems, recent injury, bleeding disorder, sugar, liver problems, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.

• It may reduce platelet counts; avoid injury or bruising.

• It may cause dizziness; do not drive a car or operate machinery while taking this medication.

• Avoid abrupt withdrawal.

• Patient may develop with increased risk of serious and life-threatening condition called thrombotic thrombocytopenic purpura (TTP) with the following symptoms: patches on the skin, fever, weakness, unusually pale skin, yellowing of the skin or eyes. If it is so consult with your doctor.

• Monitor blood pressure regularly while taking this medication.

What are the side effects of Prasugrel?

Bleeding disorders - Nose bleed, gastrointestinal bleeding, blood vomiting, bruising, post-procedural bleeding, accumulation of fluid in heart, and retinal bleeding.
Severe effects - Abnormal decrease in platelets, anemia, abnormal liver function, allergic reactions and shock.
Heart - High or low blood pressure, abnormal heart rhythm, chest pain, swelling in the heart muscles and slow heart rate.
Central Nervous System - Headache, fatigue and dizziness.
Metabolic - Increase in blood cholesterol.
Miscellaneous - Back pain, difficulty in breathing, nausea, vomiting, cough, rash, fever, swelling in the extremities, and diarrhea.

What are the other precautions for Prasugrel?

Avoid excess dosage.

What are the storage conditions for Prasugrel?

Store it at room temperature (20 to 25°C), and in an airtight container.
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