Trade Names/Brand Names :
Why it is prescribed :
This medication is an anti-angiogenic and immunomodulator, prescribed for multiple myeloma.
When it is not to be taken (Contraindications):
Contraindicated to pregnant women.
Category X :
Animal and/or human studies have demonstrated fetal injury and potential risks outweigh the benefits of the drug in pregnancy. These drugs are found to be harmful when taken during pregnancy, and should not be used.
Dosage & When it is to be taken (Indications):
4 mg per day taken orally on days 1-21 of repeated 28-day cycles until disease progression.
How it should be taken :
It comes as a capsule to take by mouth, without food, at least two hours before or two hours after a meal.
Warnings and Precautions :
• Caution should be exercised in patients with history of smoking, any other medical condition, any allergy, who are taking other medications, during pregnancy and breastfeeding.
Monitor complete blood counts regularly while taking this medication.
Side Effects :
• Most Common
Fatigue, weakness, decrease in white blood cells, anemia, constipation, nausea, diarrhea, difficulty in breathing, upper-respiratory tract infections, back pain and fever.
Pneumonia, urinary tract infection.
Musculoskeletal pain, chest pain, muscle spasms, joint pain, pain in extremity, muscular weakness, bone pain.
Difficulty in breathing, cough, nosebleed.
Decreased appetite, increase in blood minerals.
Excess sweat, rash, night sweats, dry skin, itching.
• Central Nervous System
Dizziness, tremor, headache, neuropathy peripheral, sleeplessness, confusion, anxiety.
• Lab Tests
Blood creatinine increased, weight increased or decreased.
Other Precautions :
Avoid excess dosage.
Storage Conditions :
Store it at room temperature (20°C to 25°C)