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Generic Name : Polifeprosan 20 with Carmustine
Pronunciation : kar-MUS-teen-poh-LIF-eh-pro-sin
Trade Name(s):
International- Gliadel. This medication is an antineoplastic agent, prescribed for brain cancer along with other procedures. When it is not to be taken (Contraindications):
When it is to be taken : The recommended dose is 8 wafers (polifeprosan 20 with 7.7 mg of carmustine, resulting in a dose of 61.6 mg). How it should be taken : It comes as pouched wafers to be placed into the resection cavity. Special Instruction : * Caution should be exercised in patients who are receiving other cancer chemotherapy or undergoing radiation therapy, any allergy, during pregnancy and breastfeeding. * It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication. Side Effects : Body as A Whole - Aggravation reaction, headache, weakness, infection, fever, pain, abdominal pain, back pain, face swelling, abscess, accidental injury, chest pain, allergic reactions. Heart - Blood clots, bleeding. Gastrointestinal - Nausea, vomiting, constipation, diarrhea. Metabolic - Liver function tests abnormal, diabetes, Cushing’s syndrome, healing abnormal, swelling in the extremities. Musculoskeletal - Muscle weakness. Central Nervous System - Convulsion, confusion, brain swelling, depression, drowsiness, speech disorder, memory loss, stroke, personality disorder, anxiety, facial paralysis, nerve disease, tingling, thinking abnormality, abnormal gait, dizziness, grand mal convulsion, hallucinations, sleeplessness, tremor, coma, incoordination, decreased body movement. Respiratory - Pneumonia, difficulty in breathing. Skin - Rash, hair loss. Eye - Eye swelling, abnormal vision, eye disorder, double vision. Genitourinary - Urinary tract infection, urinary incontinence. * Avoid excess dosage. Storage Conditions : Store the medication in a freezer. |
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