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Plicamycin

Latest prescription information about Plicamycin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Plicamycin
Pronunciation : plye kay mye' sin
Therapeutic Classification : Chemotherapy
Trade Name(s): 
International- Mithracin.
Why it is prescribed (Indications) : 
This medication is an antineoplastic agent, prescribed for testicular cancer, paget's disease of bone and hypercalcemia.

When it is not to be taken (Contraindications): 


Contraindicated in patients with decrease in platelets, clotting disorder and hypersensitivity.

Pregnancy Category :

A B C D X
Category X : Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.


When it is to be taken : 
IV- The recommended daily dose is 25 to 30 mcg (0.025-0.030 mg) per kilogram of body weight.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the vein.
Special Instruction : 
* Caution should be exercised in patients with history of liver or kidney disease, bone marrow depression, or bleeding disorder, any allergy, who are taking other medications, during pregnancy and breastfeeding.
Side Effects : 
Most Common - Loss of appetite, nausea, vomiting, diarrhea, mouth ulcer, fever, drowsiness, weakness, lethargy, uneasiness, headache, depression, vein inflammation, facial flushing, and skin rash.
Blood - Decrease in platelet counts.
Liver - Abnormal liver function.
Genitourinary - Increased Blood Urea Nitrogen.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature.

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