Plicamycin - Drug Information

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General Information on Plicamycin

Generic Name : Plicamycin

Pronunciation : plye kay mye' sin

Latest prescription information about Plicamycin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y43.3 | Therapeutic Classification : Antibiotics

Trade Names/Brand Names of Plicamycin

International- Mithracin.

Why is Plicamycin Prescribed? (Indications)

This medication is an antineoplastic agent, prescribed for testicular cancer, paget's disease of bone and hypercalcemia.  It interferes with the growth of cancer cells.

When should Plicamycin not to be taken? (Contraindications)

Contraindicated in patients with decrease in platelets, clotting disorder and hypersensitivity.

Pregnancy Category

A B C D X

Category X :

Animal and/or human studies have demonstrated fetal injury and potential risks outweigh the benefits of the drug in pregnancy. These drugs are found to be harmful when taken during pregnancy, and should not be used.

What is the dosage of Plicamycin?

IV- The recommended daily dose is 25 to 30 mcg (0.025-0.030 mg) per kilogram of body weight.

How should Plicamycin be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Plicamycin?

Caution should be exercised in patients with history of liver or kidney disease, bone marrow depression, or bleeding disorder, any allergy, who are taking other medications, during pregnancy and breastfeeding.

What are the side effects of Plicamycin?

   Most Common : Loss of appetite, nausea, vomiting, diarrhea, mouth ulcer, fever, drowsiness, weakness, lethargy, uneasiness, headache, depression, vein inflammation, facial flushing, and skin rash.
   Blood : Decrease in platelet counts.
   Liver : Abnormal liver function.
   Genitourinary : Increased Blood Urea Nitrogen.

What are the other precautions for Plicamycin?

Avoid excess dosage.

What are the storage conditions of Plicamycin?

Store it at room temperature.

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