Pimavanserin - Drug Information

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Last Updated : 10/12/2016

General Information on Pimavanserin

Generic Name : Pimavanserin

Latest prescription information about Pimavanserin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Trade Names/Brand Names of Pimavanserin

Nuplazid

Why is Pimavanserin Prescribed? (Indications)

Pimavanserin is an atypical antipsychotic drug which is prescribed for the treatment of hallucinations and delusions in patients with Parkinson disease-associated psychosis. 

When should Pimavanserin not to be taken? (Contraindications)

Pimavanserin should be avoided in patients who are allergic to the drug, with the use of certain medication, in patients with irregular heart rhythms or liver disease, during pregnancy and breast feeding.

What is the dosage of Pimavanserin?

The recommended dose of pimavanserin is 34mg to be taken as two 17 mg tablets twice a day. It can be taken either with food or on an empty stomach.

How should Pimavanserin be taken?

Pimavanserin comes in the form of a tablet to be taken orally by mouth.

What are the warnings and precautions for Pimavanserin?

• Patients with heart rhythm problems should not take pimavanserin.
• Women planning pregnancy should not take the drug as it may harm the fetus.

What are the side effects of Pimavanserin?

  General: Swelling of the hands, feet and ankle, walking difficulties.
  Gastrointestinal: Nausea,constipation.
  Central Nervous System: Confusions, hallucinations.

What are the other precautions for Pimavanserin?

• Pimavanserin should not be used by elderly patients with dementia-related psychosis.

What are the Drug Interactions of Pimavanserin?

Pimavanserin should be avoided with:

Drugs that Prolong QT interval:

• Antiarrhythmic drugs like quinidine, procainamide, disopyramide, sotalol, amiodarone when taken along with pimavanserin may increase the risk of arrhythmia (abnormal heart rhythm).

• Antipsychotics like ziprasidone, thioridazone and chlorpromazine and antibiotics like gatifloxacin and moxifloxacin when taken with pimavanserin may also increase the risk of arrhythmia.

CYP3A4 Inhibitors:

• Drugs like clarithromycin, itraconazole, ketoconazole and indinavir taken along with pimavanserin may increase the blood concentration of the drug.

CYP3A4 Inducers:

• Drugs like carbamazepine, rifampin and phenytoin with pimavanserin may decrease the concentration of the drug.

What are the storage conditions of Pimavanserin?

Store the medicine in a tightly closed container at room temperature. Keep out of reach of children. Protect from excess heat and moisture.

Last Updated : 10/12/2016

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