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Phentolamine Mesylate

Latest prescription information about Phentolamine Mesylate. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Phentolamine Mesylate
Pronunciation : fen-TOL-a-meen MES-i-late
Trade Name(s): 
India- Fentanor Inj, Phentosol Amp.
International- Rogitine, Phentolamine Mesylate.
Why it is prescribed (Indications) : 
This medication is a reversal anesthesia used in dental procedures for anesthetizing soft tissues (lip and tongue). It is an antihypertensive, prescribed for prevention or control of hypertension. Not recommended for children less than 6 years and weight less than 15kg (33lbs).

When it is not to be taken (Contraindications): 


Contraindicated in patients with heart attack, fast heart rate, and hypersensitivity to this drug.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
Adult: IV- The recommended dose is 2 to 5mg. Repeat if needed.
How it should be taken : 
It comes as a solution for injection, administered by healthcare providers into the vein or muscle.
Special Instruction : 
*Caution should be exercised in patients with history of fast heart rate; peptic ulcer disease; pregnancy and breastfeeding.
*Discontinue if symptoms of heart disease occur or worsen.
Side Effects : 
Most Common- Sweating, feelings of apprehension, orthostatic hypotension (sudden decline in the blood pressure when a person stands up suddenly after long hours of rest), flushing, weakness, dizziness, facial swelling, jaw and oral pain.
Heart- Fast heart rate, abnormal heart rhythm, chest pain.
Respiratory - Nasal stuffiness.
Gastrointestinal- Nausea, vomiting, diarrhea.
Potentially Fatal- Heart attack, confusion, severe or sudden headache, sudden loss of coordination, sudden slurring of speech.
Other Precautions : 
*Avoid using contaminated solution of this medication.
Storage Conditions : 
Injection: Use the reconstituted solution immediately after preparation and should not be stored. Store unopened vials at controlled room temperature (25°C).

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