Pentoxifylline - Drug Information

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General Information on Pentoxifylline

Generic Name : Pentoxifylline

Pronunciation : pen tox I' fi leen

Latest prescription information about Pentoxifylline. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y44.2 | Therapeutic Classification : Anticoagulants / Antithrombotics

Trade Names/Brand Names of Pentoxifylline

India : 

International : 

Pentoxil, Trental

Why is Pentoxifylline Prescribed? (Indications)

This medication is a xanthine derivative, prescribed for intermittent claudication (pain, cramping, numbness, or weakness in the foot, hip, thigh, or buttocks) due to poor blood circulation. It decreases the thickness of blood.

When should Pentoxifylline not to be taken? (Contraindications)

Contraindicated in patients with recent stroke, intolerance to methylxanthines such as caffeine, theophylline, theobromine and hypersensitivity.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Pentoxifylline?

PO- The usual dosage is one tablet (400 mg) three times a day with meals.

How should Pentoxifylline be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Pentoxifylline?

Caution should be exercised in patients with history of ulcers, blood vessel problems, high blood pressure, kidney problems, bleeding in the eye, any allergy, who are other medications, during pregnancy and breastfeeding.
It may cause dizziness or blurred vision, do not drive a car or operate machinery while taking this medication.

What are the side effects of Pentoxifylline?

   Heart : Chest pain, abnormal heart rhythm, palpitations and flushing.
   Gastrointestinal : Abdominal discomfort, belching, flatulence, diarrhea, indigestion, nausea and vomiting.
   Central Nervous System : Agitation, nervousness, dizziness, drowsiness, headache, sleeplessness, tremor and blurred vision.

What are the other precautions for Pentoxifylline?

Avoid excess dosage.

What are the storage conditions of Pentoxifylline?

Store it at room temperature, away from direct sunlight.


Schedule : H

Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.

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