Medindia » Consumer Health » Medication Manual » Pentosan Polysulfate sodium

Pentosan Polysulfate sodium

Latest prescription information about Pentosan Polysulfate sodium. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Email Email Save this page Save Syndicate Syndicate
Generic Name : Pentosan Polysulfate sodium
Pronunciation : PEN-toe-san pol-ee-SUL-fate SOE-dee-um
Trade Name(s): 
India- Comfora.
International- Elmiron.
Why it is prescribed (Indications) : 
This medication is a semi-synthetically produced heparin-like macro molecular carbohydrate derivative, prescribed for interstitial cystitis/painful bladder syndrome (IC/PBS).

When it is not to be taken (Contraindications): 


Hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.


When it is to be taken : 
The recommended dose is 300 mg/day taken as one 100 mg capsule orally three times daily.
How it should be taken : 
It comes as a capsule to take by mouth, at least 1 hour before meals or 2 hours after meals.
Special Instruction : 
* Caution should be exercised in patients with history of aneurysm, hemophilia, ulcers, low platelet count, an intestinal blockage, liver or spleen disease, any allergy, who are taking other medication, during pregnancy and breastfeeding.
* It may cause increased bleeding, avoid bruising or injury.
Side Effects : 
Serious- Abdominal pain, diarrhea and dehydration.
Central Nervous System - Sleeplessness, headache, severe emotional lability, depression, night blindness, dizziness and hyperactivity.
Gastrointestinal- Nausea, diarrhea, indigestion, jaundice and vomiting.
Skin- Rash, itching, tears, nose inflammation and increased sweating.
Miscellaneous- Absence of menstrual periods, joint pain and vaginal inflammation.
Other Precautions : 
*Avoid excess dosage.
Storage Conditions : 
Store it at controlled room temperature 15°-30°C.

Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.

Browse the Drugs alphabetically

Drugs Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Price List