Pentobarbital - Drug Information

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General Information on Pentobarbital

Generic Name : Pentobarbital

Pronunciation : pen toe bar' bi tal

Latest prescription information about Pentobarbital. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y47.0 | Therapeutic Classification : Sedative-hypnotic Drugs

Trade Names/Brand Names of Pentobarbital

International- Nembutal.

Why is Pentobarbital Prescribed? (Indications)

This medication is a barbiturate, prescribed for insomnia and seizures.  It slows the activities of brain and nervous system.

When should Pentobarbital not to be taken? (Contraindications)

Contraindicated in patients with history of manifest or latent porphyria (hidden genetic disorder) and hypersensitivity.

Pregnancy Category

A B C D X

Category D :

There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.

What is the dosage of Pentobarbital?

Dose is based patient’s condition.
IM- Adult- The recommended dosage ranges from 50 to 200 mg as a single dose.
Child- The recommended dosage ranges from 2 to 6 mg/kg as a single dose; Maximum- 100 mg.
IV- The recommended initial dose for the 70 kg adult is 100 mg.

How should Pentobarbital be taken?

It comes as a solution for injection to be administered by a healthcare provider into the large muscle or into the vein.

What are the warnings and precautions for Pentobarbital?

• Caution should be exercised in patients with history of liver or kidney disease, asthma, hyperthyroidism, diabetes, anemia, history of alcoholism or drug abuse, heart or lung problems, any allergy, who are taking other medications, children, elderly, during pregnancy and breastfeeding.
• Avoid rapid intravenous administration; otherwise it may cause respiratory depression.
• Avoid long-term use of this medication; otherwise patient may get addicted to this drug.
• Avoid alcohol consumption.
• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

What are the side effects of Pentobarbital?

•   Most Common : Drowsiness.
•   Central Nervous system : Agitation, confusion, incoordiation, depression, abnormal dreams, nervousness, mental disturbances, hallucinations, sleeplessness, anxiety, dizziness and thinking abnormality.
•   Respiratory : Respiratory depression and shortness of breathing.
•   Heart : Slow heart rate, low blood pressure and fainting.
•   Gastrointestinal : Nausea, vomiting and constipation.
•   Hypersensitivity reactions : Shock, skin rashes and skin inflammation.
•   Miscellaneous : Headache, injection site reactions, fever, liver damage and anemia

What are the other precautions for Pentobarbital?

Avoid excess dosage.

What are the storage conditions of Pentobarbital?

Store it at controlled room temperature (15-30°C).


Schedule : X

Narcotic and Psychotropic drugs which cannot be sold without the prescription of a Registered Medical Practitioner.

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etechmaster 

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