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Pentobarbital

Latest prescription information about Pentobarbital. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Pentobarbital
Pronunciation : pen toe bar' bi tal
Trade Name(s): 
International- Nembutal.
Why it is prescribed (Indications) : 
This medication is a barbiturate, prescribed for insomnia and seizures.

When it is not to be taken (Contraindications): 


Contraindicated in patients with history of manifest or latent porphyria (hidden genetic disorder) and hypersensitivity.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
Dose is based patient’s condition.
IM- Adult- The recommended dosage ranges from 50 to 200 mg as a single dose.
Child- The recommended dosage ranges from 2 to 6 mg/kg as a single dose; Maximum- 100 mg.
IV- The recommended initial dose for the 70 kg adult is 100 mg.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the large muscle or into the vein.
Special Instruction : 
* Caution should be exercised in patients with history of liver or kidney disease, asthma, hyperthyroidism, diabetes, anemia, history of alcoholism or drug abuse, heart or lung problems, any allergy, who are taking other medications, children, elderly, during pregnancy and breastfeeding.
* Avoid rapid intravenous administration; otherwise it may cause respiratory depression.
* Avoid long-term use of this medication; otherwise patient may get addicted to this drug.
* Avoid alcohol consumption.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
Side Effects : 
Most Common - Drowsiness.
Central Nervous system - Agitation, confusion, incoordiation, depression, abnormal dreams, nervousness, mental disturbances, hallucinations, sleeplessness, anxiety, dizziness and thinking abnormality.
Respiratory - Respiratory depression and shortness of breathing.
Heart - Slow heart rate, low blood pressure and fainting.
Gastrointestinal - Nausea, vomiting and constipation.
Hypersensitivity reactions - Shock, skin rashes and skin inflammation.
Miscellaneous - Headache, injection site reactions, fever, liver damage and anemia
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at controlled room temperature (15-30°C).

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