Pentazocine and Naloxone - Drug Information

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General Information on Pentazocine and Naloxone

Generic Name : Pentazocine and Naloxone

Pronunciation : pen taz' oh seen- nal ox' one

Latest prescription information about Pentazocine and Naloxone. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y45.8 | Therapeutic Classification : Analgesics

Trade Names/Brand Names of Pentazocine and Naloxone

International- Talwin NX.

Why is Pentazocine and Naloxone Prescribed? (Indications)

This combination medication is an analgesic, prescribed for moderate to severe pain. It inhibits the action of the substances that cause pain.  

When should Pentazocine and Naloxone not to be taken? (Contraindications)

Hypersensitivity.

Pregnancy Category

A B C D X

Category D :

There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.

What is the dosage of Pentazocine and Naloxone?

Adults- The usual initial adult dose is 1 tablet every three or four hours. This may be increased to 2 tablets when needed. Total daily dosage should not exceed 12 tablets.

How should Pentazocine and Naloxone be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Pentazocine and Naloxone?

Caution should be exercised in patients with history of electrolyte imbalance, breathing problems, high blood pressure, heart disease, under active thyroid, Addison disease, liver or kidney disease, enlarged prostate, trouble in urinating, porphyria, stomach problems, any allergy, who are taking other medications, during pregnancy and breastfeeding.
It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.
Avoid alcohol consumption.

What are the side effects of Pentazocine and Naloxone?

   Central Nervous System : Drowsiness, dizziness, lightheadedness, nervousness, apprehension, depression, floating feeling, headache, weakness, faintness, disturbed dreams and sleeplessness.
   Gastrointestinal : Nausea, vomiting and constipation.
   Heart : High or low blood pressure, fast heart rate and poor blood circulation.
   Metabolic : Increased sweating, flushing of the skin, dry mouth and altered taste.
   Allergic reactions : Swelling of the face, shock, skin inflammation, itching, flushed skin, rash and hives.
   Eye : Blurred vision and difficulty in focusing.

What are the other precautions for Pentazocine and Naloxone?

Avoid excess dosage.

What are the storage conditions of Pentazocine and Naloxone?

Store it at room temperature.

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