Pentazocine - Drug InformationGeneric Name : Pentazocine | Pronunciation : pen-TAZ-oh-seen
Latest prescription information about Pentazocine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Why it is prescribed (Indications) :
This medication relieves moderate to severe pain. It is an opioid (narcotic) analgesic. It works in the brain and nervous system to decrease pain.
When it is not to be taken (Contraindications):
Contraindicated in patients with head injury, increased blood pressure or pulmonary hypertension, patients dependent on opioids, heart failure, respiratory depression, heart attack and raised intracranial pressure. It should also not be used for a long time or in increased amounts at term during pregnancy.
Pregnancy Category :
Category D :There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Dosage & When it is to be taken :
Adult: 50-100 mg every 3 to 4 hrs; max 600 mg daily.
Child: 6 to12 yr: As hydrochloride: 25 mg every 3 to 4 hr.
How it should be taken :
It comes as a solution for injection, to be administered by a healthcare provider into the vein or large muscle.
Warnings and Precautions :It may cause drowsiness or dizziness. Avoid driving or handling of machines while taking this drug.
Avoid drinking alcohol or taking other medications that cause drowsiness while using this medication.
It may cause allergic reaction if it contains sulfides.
Inform your doctor about previous dental treatment.
Caution needed for elderly people.
Side Effects :
Heart- Circulatory depression, high blood pressure, shock, fast heart rate.
Central Nervous System- Confusion, depression, disorientation, disturbed dreams, dizziness, excitement, faintness, hallucinations, headache, sleeplessness, irritability, light-headedness, muscle tremor, tingling, sedation, temporary loss of consciousness, tremor, weakness.
Skin- Inflammation, including itching, excessive sweating, flushed skin.
Eye and ENT- Double vision, constriction of the pupil, involuntary eye movement, perception of sound, visual blurring, and focusing difficultly.
Gastrointestinal- Constipation, cramps, diarrhea, dry mouth, nausea, taste alteration, vomiting.
Blood- High concentration of eosinophils decrease in the number of granulocytes.
Skin- Subcutaneous depression, nodules, severe stiffness, soft tissue induration, sting on injection, and ulceration at injection sites.
Respiratory- Difficulty in breath, respiratory depression, transient sleep disorder in newborns whose mothers received parenteral pentazocine during labor.
Miscellaneous- Allergic reactions, alterations in rate or strength of uterine contractions during labor, chills, urinary retention, unusual weakness.