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Pegaspargase

Latest prescription information about Pegaspargase. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Pegaspargase
Pronunciation : peg-AS-par-jase
Therapeutic Classification : Chemotherapy
Trade Name(s): 
International- Oncaspar.
Why it is prescribed (Indications) : 
This medication is an antineoplastic agent, prescribed for acute lymphoblastic leukemia (ALL).

When it is not to be taken (Contraindications): 


Contraindicated in patients with serious blood clots, bleeding disorder, chickenpox, shingles, or inflammation of the pancreas, and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
IM/IV- The recommended dose is 2,500 IU/m2.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the vein or muscle.
Special Instruction : 
* Caution should be exercised in patients with history of liver problems, bone marrow problems, sugar, infection, undergoing radiation therapy, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may raise blood sugar level; monitor sugar level regularly while taking this medication.
* It may reduce platelet counts; avoid injury or bruising.
Side Effects : 
Most Common - Allergic reactions (including anaphylaxis), increased sugar, blood clotting disorder, increase in liver enzyme, inflammation of pancreas, and stroke.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it in refrigerator (2 to 8°C), do not freeze it.

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