Trade Names/Brand Names :
Paxil, Paxil CR, Pexeva
Why it is prescribed :
This medication is an SSRI antidepressant, prescribed for major depression, obsessive-compulsive disorder, panic disorder, social anxiety and generalized anxiety disorder. It increases the amount of serotonin, a natural substance in the brain that helps maintain mental balance.
When it is not to be taken (Contraindications):
Contraindicated in patients who are taking monoamine oxidase inhibitors (MAOIs), pimozide, and hypersensitivity.
Category D :
There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.
Dosage & When it is to be taken (Indications):
PO- The recommended initial dose is 20 mg/day.
How it should be taken :
It comes as a tablet and liquid to take by mouth, with or without food.
Warnings and Precautions :
• Caution should be exercised in patients with history of increased eye pressure, seizures, stomach bleeding, liver, kidney or heart disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.
It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
Avoid alcohol consumption.
Patient may develop with increased risk of Neuroleptic malignant syndrome (NMS) and Serotonin Syndrome
with the following symptoms: fever, rigid muscles, blood pressure changes, mental changes, restlessness, diarrhea, fast heart beat, incoordination, nausea, vomiting. If it is so consult with your doctor.
Side Effects :
• Most Common
Weakness, sweating, nausea, decreased appetite, drowsiness, dizziness, sleeplessness, tremor, nervousness, ejaculatory disturbance, and other male genital disorders.
• Body as a Whole
Palpitations and dilatation of blood vessels.
Sweating and rash.
Nausea, dry mouth, constipation, diarrhea, decreased appetite, flatulence and indigestion.
Muscle pain and weakness.
• Central Nervous System
Anxiety, tingling, decreased sexual activity and confusion.
• Eye and ENT
Respiration problems, blurred vision and taste perversion.
Ejaculatory disturbances, urinary frequency, urination disorder and female genital disorders.
Other Precautions :
Avoid excess dosage.
Storage Conditions :
Store it at room temperature, away from direct sunlight and excess heat and moisture.
♦ Safety Labeling Changes Approved By FDA