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Paroxetine

Updated on : April - 2012
Latest prescription information about Paroxetine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Paroxetine
Pronunciation : pa rox' e teen
Therapeutic Classification : Psychotherapeutics
ICD Code : Y49.2
Trade Name(s): 
India- Cinpar-Cr, Deprox, Leparox, Oxitine-Cr, Oxitine-Pr, Panex, Paradise X, Pari, Pari Cr, Parim Cr, Parogen-Cr, Parotin, Paroxet-10, Paroxet-20, Paxidep, Petin Cr, Pexep, Praxir, Prx, Pxt, Raxit, Sarolife, Xet.
International- Paxil, Paxil CR, Pexeva.
Why it is prescribed (Indications) : 
This medication is an SSRI antidepressant, prescribed for major depression, obsessive-compulsive disorder, panic disorder, social anxiety and generalized anxiety disorder. It increases the amount of serotonin, a natural substance in the brain that helps maintain mental balance.
When it is not to be taken (Contraindications): Contraindicated in patients who are taking monoamine oxidase inhibitors (MAOIs), pimozide, and hypersensitivity.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
PO- The recommended initial dose is 20 mg/day.
How it should be taken : 
It comes as a tablet and liquid to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of increased eye pressure, seizures, stomach bleeding, liver, kidney or heart disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* Patient may develop with increased risk of Neuroleptic malignant syndrome (NMS) and Serotonin Syndrome with the following symptoms: fever, rigid muscles, blood pressure changes, mental changes, restlessness, diarrhea, fast heart beat, incoordination, nausea, vomiting. If it is so consult with your doctor.
Side Effects : 
Most Common - Weakness, sweating, nausea, decreased appetite, drowsiness, dizziness, sleeplessness, tremor, nervousness, ejaculatory disturbance, and other male genital disorders.
Body as a Whole - Headache.
Heart - Palpitations and dilatation of blood vessels.
Skin - Sweating and rash.
Gastrointestinal - Nausea, dry mouth, constipation, diarrhea, decreased appetite, flatulence and indigestion.
Musculoskeletal - Muscle pain and weakness.
Central Nervous System - Anxiety, tingling, decreased sexual activity and confusion.
Eye and ENT - Respiration problems, blurred vision and taste perversion.
Genitourinary - Ejaculatory disturbances, urinary frequency, urination disorder and female genital disorders.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature, away from direct sunlight and excess heat and moisture.
♦ Safety Labeling Changes Approved By FDA

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Member Comments ( 4 )
I'm 25 years, male from Mauritius and I'm taking Pari LP twice a day since 1 month and I'm having a problem. I'm not ejaculating while masturbing or having sexual intercourse. Is it the medicine please?
(Posted by Washim, Mauritius Date : 6/17/2012 )
For how long can I take PAROXETINE?
I also take RISPERIDONE
Can my speech be affected by these drugs?
ANNA 18/8/2010

(Posted by malgosia1, United Kingdom Date : 8/18/2010 )
sir,
I have been taking paroxetine "paradise torrent",for more then 34 months ,what may be the reason ,why my doc is not saying ,not to take anymore of it?
I had gone through a real big shocking experience previously.but now I am fine ,and in a great shape.
pl.suggest .......
thanks.....[I DO believe on my doc`s opinion]
lalit joshi

(Posted by lalitji, India Date : 3/28/2010 )
Can we take paroxetine again some time after a treatment?and for how long
(Posted by steeve osman, Mauritius Date : 11/29/2008 )

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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