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Palonosetron

Latest prescription information about Palonosetron. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Palonosetron
Pronunciation : PAL-oh-NOE-se-tron
Trade Name(s): 
India- Palnox, Palonew, Palzen, Themiset.
International- Aloxi.
Why it is prescribed (Indications) : 
This medication is 5-HT3 receptor blocker, prescribed for prevention of chemotherapy-induced nausea and vomiting.

When it is not to be taken (Contraindications): 


Hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.


When it is to be taken : 
Dosage for Adults – IV- A single 0.25 mg dose is administered over 30 seconds.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the vein.
Special Instruction : 
* Caution should be exercised in patients with history of heart disease, decrease in blood minerals, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
* It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.
Side Effects : 
Most Common - Headache, constipation, diarrhea, dizziness, fatigue, abdominal pain and sleeplessness.
Heart - Fast heart rate, slow heart rate, low or high blood pressure, abnormal heart rhythm and heart attack.
Skin - Skin inflammation and rash.
Eye and ENT - Motion sickness, ringing in the ear, eye irritation and vision abnormality.
Gastrointestinal - Indigestion, dry mouth, hiccups and flatulence.
General - Weakness, fever, hot flash and flu-like syndrome.
Liver - Increase in liver enzymes level.
Metabolic - Increase in blood minerals and sugar, loss of appetite and acidity.
Musculoskeletal - Joint pain.
Central Nervous System - Drowsiness, sedation, tingling, anxiety and emotions.
Genitourinary - Urinary retention.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at controlled temperature (20-25°C). Protect from light.

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