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Generic Name : Palonosetron
Pronunciation : PAL-oh-NOE-se-tron
Trade Name(s):
India- Palnox, Palonew, Palzen, Themiset. International- Aloxi. This medication is 5-HT3 receptor blocker, prescribed for prevention of chemotherapy-induced nausea and vomiting. When it is not to be taken (Contraindications):
When it is to be taken : Dosage for Adults – IV- A single 0.25 mg dose is administered over 30 seconds. How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the vein. Special Instruction : * Caution should be exercised in patients with history of heart disease, decrease in blood minerals, any allergy, who are taking other medications, children, during pregnancy and breastfeeding. * It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication. Side Effects : Most Common - Headache, constipation, diarrhea, dizziness, fatigue, abdominal pain and sleeplessness. Heart - Fast heart rate, slow heart rate, low or high blood pressure, abnormal heart rhythm and heart attack. Skin - Skin inflammation and rash. Eye and ENT - Motion sickness, ringing in the ear, eye irritation and vision abnormality. Gastrointestinal - Indigestion, dry mouth, hiccups and flatulence. General - Weakness, fever, hot flash and flu-like syndrome. Liver - Increase in liver enzymes level. Metabolic - Increase in blood minerals and sugar, loss of appetite and acidity. Musculoskeletal - Joint pain. Central Nervous System - Drowsiness, sedation, tingling, anxiety and emotions. Genitourinary - Urinary retention. * Avoid excess dosage. Storage Conditions : Store it at controlled temperature (20-25°C). Protect from light. |
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