Paclitaxel - Drug Information

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General Information on Paclitaxel

Generic Name : Paclitaxel

Pronunciation : Pack-lee-Tax-el

Latest prescription information about Paclitaxel. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Why is Paclitaxel Prescribed? (Indications)

This medication is a chemotherapy agent, prescribed for ovarian and breast cancer. It slows or stops cancer cell growth.

When should Paclitaxel not to be taken? (Contraindications)

Contraindicated in patients with extremely low white blood cell counts and hypersensitivity.

Pregnancy Category

A B C D X

Category D :

There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.

What is the dosage of Paclitaxel?

Adult- IV- The recommended dose is 135 to 175 mg/m2, over 3 hours every 3 weeks for 4 courses.

How should Paclitaxel be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Paclitaxel?

Caution should be exercised in patients with history of viral infection, HIV infection, heart, liver or kidney problems, bone marrow depression, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
It may cause dizziness or vision changes, do not drive a car or operate machinery while taking this medication.
Avoid alcohol consumption.
It may reduce platelet counts; avoid injury or bruising.

What are the side effects of Paclitaxel?

   Heart : Abnormal ECG, high blood pressure and slow heart rate.
   Central Nervous System : Nerve damage.
   Skin : Hair loss.
   Gastrointestinal : Nausea, vomiting, and diarrhea.
   Blood : Anemia, decrease in white blood cells, platelets and bleeding.
   Liver : Elevated liver enzyme levels.
   Hypersensitivity : Severe allergic reactions such as rash, hives, trouble in breathing, etc.
  Eye:Cystoid macular edema (CME).
   Local : Injection site reaction.
   Musculoskeletal : Muscle and joint pain.
   Miscellaneous : Bone marrow infections.

What are the other precautions for Paclitaxel?

Avoid excess dosage.

What are the storage conditions of Paclitaxel?

Store it at room temperature and in an airtight container.

♦ Safety Labeling Changes Approved By FDA

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