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Paclitaxel

Latest prescription information about Paclitaxel. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Paclitaxel
Pronunciation : Pack-lee-Tax-el
Therapeutic Classification : Chemotherapy
Trade Name(s): 
India- Abraxane, Altaxel, Betaxel, Cansure, Cantaxelm Cytax, Dutaxel, Intaxel, Mitotax, N-anosel, Napro-tax, Neotaxl, Oncotaxel, Paclicad, Pacliron, Paclitec, Paclitrust, Paxtal, Paxytol, Petaxel, Taxol.
International- Abraxane, Onxol.
Why it is prescribed (Indications) : 
This medication is a chemotherapy agent, prescribed for ovarian and breast cancer.

When it is not to be taken (Contraindications): 


Contraindicated in patients with extremely low white blood cell counts and hypersensitivity.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
Adult- IV- The recommended dose is 135 to 175 mg/m2, over 3 hours every 3 weeks for 4 courses.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the vein.
Special Instruction : 
* Caution should be exercised in patients with history of viral infection, HIV infection, heart, liver or kidney problems, bone marrow depression, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* It may cause dizziness or vision changes, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* It may reduce platelet counts; avoid injury or bruising.
Side Effects : 
Heart - Abnormal ECG, high blood pressure and slow heart rate.
Central Nervous System - Nerve damage.
Skin - Hair loss.
Gastrointestinal - Nausea, vomiting, and diarrhea.
Blood - Anemia, decrease in white blood cells, platelets and bleeding.
Liver - Elevated liver enzyme levels.
Hypersensitivity - Severe allergic reactions such as rash, hives, trouble in breathing, etc.
Local - Injection site reaction.
Musculoskeletal - Muscle and joint pain.
Miscellaneous - Bone marrow infections.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature and in an airtight container.

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