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Oxybutynin Hydrochloride

Updated on : March - 2012
Latest prescription information about Oxybutynin Hydrochloride. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Oxybutynin Hydrochloride
Pronunciation : ox i byoo' ti nin
Therapeutic Classification : Anticholinergics
ICD Code : Y51.3
Trade Name(s): 
India- Cystran, Noctorin, Oxybutin, Oxyspas, Tropan.
International- Ditropan, Ditropan XL, Oxytrol.
Why it is prescribed (Indications) : 
This medication is an antispasmodic, anticholinergic drug, prescribed for urinary incontinence and frequent urination. It works by relaxing the bladder muscles to prevent urinary urgency.
When it is not to be taken (Contraindications): Contraindicated in patients with urinary retention, gastric retention, uncontrolled eye pressure and hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : 
Adult: PO- 2.5-5 mg 2-3 times/day. Max: 5 mg 4 times/day if needed.
Transdermal Per patch delivering 3.9 mg/day: Apply 1 patch to abdomen, hip or buttock twice weekly.
How it should be taken : 
It comes as a tablet and capsule to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of heart disease, high blood pressure, nervous disease, liver or kidney disease, myasthenia gravis, enlarged prostate, overactive thyroid, stomach problem, hernia, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause drowsiness, dizziness, or blurred vision, do not drive a car or operate machinery while taking this medication.
* Do not become overheated in hot weather.
Side Effects : 
General - Headache, weakness and body pain.
Gastrointestinal - Dry mouth, constipation, diarrhea, nausea, indigestion, loss of appetite, difficulty in swallowing, chest discomfort, and thirst.
Central Nervous System - Drowsiness, dizziness, and headache.
Respiratory - Runny nose.
Eye and ENT - Blurred vision, dry eyes and glaucoma.
Genitourinary - Urinary tract infection.
Other Precautions : 
* Avoid alcohol consumption.
Storage Conditions : 
Store it at room temperature.
♦ Safety Labeling Changes Approved By FDA

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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