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Generic Name : Oxandrolone
Pronunciation : ox an' droe lone
Trade Name(s):
International- Oxandrin. When it is not to be taken (Contraindications): Contraindicated in patients with prostate or breast cancer in men, breast cancer in women with increased calcium level, kidney disease and hypersensitivity.
When it is to be taken : Adults –Oral: The recommended dose is 2.5 to 20 mg/day in 2 to 4 divided doses. Children –Oral: The recommended dose is 0.1 mg/kg (0.45 mg/lb) or less daily. How it should be taken : It comes as a tablet to take by mouth, with or without food. Special Instruction : * Caution should be exercised in patients with history of heart, kidney or liver disease, jaundice, enlarged prostate, breast or prostate cancer, allergy, bleeding or clotting problems, high level of cholesterol in blood, increased level of calcium in blood, who are taking anticoagulants and other drugs, during pregnancy and breastfeeding. * Monitor blood counts and liver functions regularly while taking this medication. Side Effects : In males- Prepubertal: Penis enlargement and increased frequency or persistence of erection. Post pubertal: Inhibition of testicular function, diminish in size of reproductive organs, absence of sperm cells, impotence, painful penis erection and bladder irritability. In females- Clitoral enlargement and menstrual irregularities. Central Nervous System- Habituation, excitement, sleeplessness, depression and changes in libido. Blood- Bleeding. Genitourinary- Breast enlargement in male ENT- Deepening of the voice in females. Skin- Acne, excessive hair growth over the body and baldness in females. Musculoskeletal- Premature closure of epiphyses (long bone) in children results in poor bone growth. Metabolic- Decreased glucose tolerance, change in the level of liver enzymes and swelling in the extremities. *Avoid excess dosage. Storage Conditions : Store it at room temperature (25° to 30°C), and in an airtight container. Keep away from children. |
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