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Omeprazole and Sodium Bicarbonate - Indications, Dosage, Side Effects and Precautions

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Information about Omeprazole and Sodium Bicarbonate

Generic Name : Omeprazole and Sodium Bicarbonate
Up-to-date prescription details regarding Omeprazole and Sodium Bicarbonate are provided here.

Pronunciation : oh-MEP-ra-zole- SOE-dee-um bye-KAR-bo-nate

Learn the correct pronunciation of the Omeprazole and Sodium Bicarbonate, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y53.1 Therapeutic Classification : Antacids

Trade Names/Brand Names of Omeprazole and Sodium Bicarbonate

International :


Zegerid and Zegerid OTC

Why is Omeprazole and Sodium Bicarbonate Prescribed? (Indications)

This combination medication contains proton pump inhibitor (PPI) and sodium bicarbonate, prescribed for esophagal irritation caused by gastroesophageal reflux disease (GERD).

When should Omeprazole and Sodium Bicarbonate not be taken? (Contraindications)

Hypersensitivity.
It should not be co-administered with Clopidogrel and St John’s Wort.

What is the dosage of Omeprazole and Sodium Bicarbonate?

PO- The recommended dose is 20 to 40 mg once daily for 4 to 8 weeks.

How should Omeprazole and Sodium Bicarbonate be taken?

It comes as a capsule to take by mouth, on an empty stomach at least one hour before a meal.

What are the warnings and precautions for Omeprazole and Sodium Bicarbonate?

• Caution should be exercised in patients with history of liver problems, stomach or bowel cancer, undiagnosed rectal bleeding, shortness of breath, frequent wheezing, chest pain, heartburn, Bartter syndrome, low blood minerals, osteoporosis, difficulty in swallowing, chest or shoulder pain with shortness of breath, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.

• It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.

• Avoid long-term use of this medication with calcium supplements or milk; otherwise it may cause milk-alkali syndrome.

• It should be used with extreme caution in Asian patients; the risk of side effects may be increased in these patients.

What are the side effects of Omeprazole and Sodium Bicarbonate?

Blood - Anemia, decrease in platelets.
Heart - Abnormal heart rhythm, slow heart rate, fast heart rate, high blood pressure, low blood pressure.
Gastrointestinal - Constipation, diarrhea, abnormal deficiency of movement.
General - Extreme elevation of body temperature, fluid retention.
Infections - Mouth infection, sepsis, urinary tract infection.
Metabolic - Fluid overload, increased blood sugar, increase or decrease in blood minerals.
Central Nervous System - Agitation.
Respiratory - Acute respiratory distress syndrome, pneumonia, respiratory failure.
Skin - Bedsores, rash.

What are the other precautions for Omeprazole and Sodium Bicarbonate?

Avoid excess dosage.

What are the storage conditions for Omeprazole and Sodium Bicarbonate?

Store it at controlled room temperature (25°C).
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