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Omalizumab

Latest prescription information about Omalizumab. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Omalizumab
Pronunciation : OH-ma-LIZ-oo-mab
Therapeutic Classification : Monoclonal antibodies
ICD Code : Y43.4
Trade Name(s): 
International- Xolair.
Why it is prescribed (Indications) : This medication is a recombinant monoclonal antibody, prescribed for moderate to severe asthma. It reduces the allergic responses in the body.  
When it is not to be taken (Contraindications): Hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : SC: The recommended dose is 150 to 375 mg every 2 or 4 weeks. Doses greater than 150 mg should be divided and administered at different sites.
How it should be taken : It comes as a solution for injection, to be administered by a healthcare provider under the skin.
Warnings and Precautions : 
* Caution should be exercised in patients with history of cancer, any allergy, asthma, infections, elderly, children, during pregnancy and breastfeeding.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
* Patient may develop with increased risk of infections with worms that live inside the body, if it so consult with your doctor.
Side Effects : 
Most Common- Injection site reaction, viral infections, upper respiratory tract infection, inflammation of sinus/pharynx and headache.
Body as a whole- Pain and fatigue.
Musculoskeletal- Joint/leg/arm pain and fracture.
Central Nervous system- Headache and dizziness.
Skin- Itching and inflammation.
ENT- Ear pain.
Other Precautions : 
*Avoid excess dosage.
Storage Conditions : 
Store it in refrigerator (2-8°C), do not freeze it.

Related News

Omalizumab Helps Reduce Seasonal Asthma Attacks in Children

A clinical trial has found that the drug omalizumab, sold under the brand name Xolair, nearly eliminated seasonal increases in asthma attacks and decreased asthma symptoms among inner-city children ...

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Posted by:  sunil60, India  Posted on: 10/5/2012
Please find below the treatment details what NEHA has undergone.

NAME-NEHA KOTHARI.
AGE-24 yrs
DISEASE NAME-Atopic Dermatitis

Family history is strong as diseases like asthama, thyroid, diabites, leucoderma; small allergies like sneezing n rashes are v common in the family.

I am suffering from this disease since I was three months old. Firstly doctors said that allergy is due to milk and milk products and will go at the age of 5.

Initially it was only on joints of hands and legs. It was in control.
Then I opted for homeopathy and it was almost reduced to zero for 7 yrs. The person who gave me medicine was not a professional doctor and was v old so he expired and the name of the medicine was not known.
Again when problem started a bit then I went to Mumbai and visited a homeopathic hospital where the medicine given was so reactive that my whole body was full of wounds and swelling and uncontrolled peeling of skin with severe etching.
Then I again went there and after seeing my condition the doc said to go for some antibiotics and steroids which relieved me a bit.
Patch test was done in which allergy was due to PARABEN.perfumes doesn’t suit me at all. Dryness is extreme and it was more in summers before but now whole year the condition is same.
I also took UVB treatment for 16 therapies. My doze started from 120 and went upto 890.then my skin became v dry so doctors stopped it.
After few months a new problem of Tuberculosis was detected and all the test were done. Then I took antitubercular medicine course for 8 months. TB is in full control now and no more medication required as per the doctor.
Meanwhile this skin problem increased a lot and at present every body part is under severe etching state and peeling of skin which results in wounds. My tuberculosis course ended on March 11, 2011.
Present state is worse.Loss of weight was there but now it is stable although it has reduced a lot. Presently whole body is affected n etching is very severe. Body has turned black. Peeling of skin is still too much. Presently applying baby aquaphor ointment which relieves me a bit.
Allopathic medicine taking is cyclosprin from last one year. just now dosge reduse 200 mg in week starting 150mg daily.
Posted by:  samik56, India  Posted on: 5/25/2012
please give some brand name of the drugs available in india?

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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