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Olanzapine

Updated on : August - 2012
Latest prescription information about Olanzapine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Olanzapine
Pronunciation : oh lan' za peen
Therapeutic Classification : Psychotherapeutics
ICD Code : Y49.5
Trade Name(s): 
India- Anzatric, Cinol, Cinol Fort, Cinol Plus, Dopin Tab, Dopin-F, Jolyon-Md, Joyzol, Lano, Lanopin, Manza, Meltolan, M-Olan, M-Olan Plu, Olace, Oladay, Oladay-F, Olan, Olandus, Olanex, Olanex F, Olanex Ins, Olanzapik, Olapax, Olapin, Olapin For, Olapin Plu, Olapin Tab, Oleanz, Oles, Olexar, Olima, Olima-7.5, Oliza, Oliza Inj, Olorest-F, Olpin, Oltal, Olzap, Onza, Opin, Opin Tab, Opirap, Ozace, Ozap, Ozapin Md, Pine, Pinsun, Polanz, Psychozap, Schizol Fo, Schizol Pl, Schizol-Md, Sizol, Skyzol, Tolaz, Zolo, Zolo-F, Zool-F, Zycopin, Zypine.
International- Zyprexa.
Why it is prescribed (Indications) : This medication is an atypical antipsychotic, prescribed for schizophrenia.  It changes the activity of certain natural substances in the brain.
When it is not to be taken (Contraindications): Hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
PO- Adult – The recommended initial dose is 5 to 10 mg once a day. Maintenance: 10 mg/day to 20 mg/day.
Adolescents- The recommended starting dose is 2.5 or 5 mg/day.
How it should be taken : It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of liver, stomach problems, enlarged prostate, increased eye pressure, neuroleptic malignant syndrome (NMS), lung disease, suicidal thoughts, heart attack, irregular heartbeat, seizures, obesity, breast cancer, difficulty in swallowing, high/low blood pressure, sugar, any allergy, who are taking other medications, elderly, during pregnancy and breastfeeding.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
* Avoid alcohol consumption.
* Drink adequate fluids to avoid becoming over heated or dehydration; otherwise it may cause heat stroke.
* It may raise blood sugar with increased thirsty, drowsiness or confusion; if it so consult with your doctor.
*Patient may develop Post-injection Delirium Sedation Syndrome (PDSS) within 3 hours after administration of this medication.
Side Effects : 
Body as a Whole - Weakness, back pain, accidental injury and chest pain.
Central Nervous System - Drowsiness, tremor, depression, dizziness, speech disorder, memory loss, tingling, confusion, emotion and incoordination.
Heart - High blood pressure and fast heart rate.
Gastrointestinal - Dry mouth, increased appetite/thirst, constipation and increased salivation.
Metabolic - Weight gain and swelling in the extremities.
Respiratory - Difficulty in breathing and lung inflammation.
Skin - Increased sweating, pimples and dry skin.
Eye - Abnormal vision.
Genitourinary - Painful menstrual period and vaginal infection.
Other Precautions : 
* Avoid contact with people who have infections.
Storage Conditions : 
Store it at controlled room temperature (20° - 25°C).
♦ Safety Labeling Changes Approved By FDA

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Member Comments ( 2 )
My Sister took Olanex F for 5 mg for 1 year. Though it was prescribed by the doctor for 1 month. She was very thin now become Fat. And now for 15 days she is getting Sense less instantly without getting any indication. We are very much scared for her and confused what to do next? Please advice me to get rid of this problem.

Thanks in advance

Somnath

(Posted by Somnath_Suri, India Date : 3/11/2013 )
I take oliza 10 for unused hearing therefore i want to know how many year will be take this medicine for better leving .Plz give me if any alternative way for better solutions.
(Posted by grv.bid, India Date : 1/11/2013 )

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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