Norethindrone - Drug Information

Generic Name : Norethindrone | Pronunciation : nor-ETH-in-drone
J E 4

Latest prescription information about Norethindrone. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y42.4 | Therapeutic Classification : Oral Contraceptives
Drug Information

Trade Name(s): 

India : 


International : 

Ortho Micronor , Aygestin , Nor-QD

Why it is prescribed : 

This medication is synthetic oral progestin, used for the treatment of secondary amenorrhea (absence of periods for a few months but patient is not pregnant), endometriosis (the tissue that lines the inner wall of the uterus is found at other sites), and abnormal uterine bleeding due to hormonal imbalance. It induces secretory changes in the endometrium. It works by altering the lining of the uterus.

When it is not to be taken (Contraindications): 

Contraindicated in patients with severe liver dysfunction, undiagnosed vaginal bleeding, porphyria, pregnancy, previous or current blood clot, deep vein thrombosis, and hypersensitivity.

Pregnancy Category :






Category X :

Animal and/or human studies have demonstrated fetal injury and potential risks outweigh the benefits of the drug in pregnancy. These drugs are found to be harmful when taken during pregnancy, and should not be used.

Dosage & When it is to be taken (Indications): 

Adult: Oral- The recommended usual dose is 2.5 to 10 mg/day, for 5 to 10 day during the second half of the menstrual period. Endometriosis- 5mg/day for 14days, Max: 15mg/day for 6 to 9 months.

How it should be taken : 

It comes as a tablet to take by mouth, with or without food.

Warnings and Precautions : 

Caution needed for patients with history of high blood pressure, heart disease, liver impairment, epilepsy, breastfeeding, new onset of migraine-type headache, asthma, kidney impairment, history of clinical depression.

Side Effects : 

  Most Common
- Headache, breast pain, irregular vaginal bleeding or spotting, stomach/abdominal cramps/bloating, nausea and vomiting, hair loss.

- Change in sexual interest, changes in menstrual flow, changes in cervical mucus secretion.

  Central Nervous System
- Headache, dizziness, mood swings, trouble sleeping.

- High blood pressure
- Abnormal liver tests, jaundice.

- Blurred/double vision, loss of vision.

- Hives, rash, acne, growth of hair on face, increased pigmentation.

- Increase in blood sugar, increased lipids.

- Increase in blood clots in veins.

Other Precautions : 

Do not smoke while taking this medication.

Storage Conditions : 

Oral: Keep this medication in an airtight container, and away from children. Store it at room temperature (below 25C).


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I am 37 Years Female and this month I could not get periods, so doctor suggested to take NCNORM-P & E 2 Tablets for 3 days. However still I could not get the periods. So can I take NCNORM-P & E Tablets for another 3 days or what should I do ?
pranpur  Friday, April 19, 2013
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