Information about Norepinephrine

Generic Name : Norepinephrine
Up-to-date prescription details regarding Norepinephrine are provided here.

Pronunciation : nor ep i NEF rin

Learn the correct pronunciation of the Norepinephrine, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y52 Therapeutic Classification : Cardiovascular Agents

Trade Names/Brand Names of Norepinephrine

India :

Epinor (4mg) | Veraline (2mg) | Norad 2mg Injection | Adronis (4mg/2mL) | Norad (4mg)

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International :

Levophed

Why is Norepinephrine Prescribed? (Indications)

This medication is prescribed for low blood pressure (hypotension) that can occur with certain medical conditions or surgical procedures. It is often used during CPR (cardio-pulmonary resuscitation). It is a catecholamine with multiple roles including as a hormone and a neurotransmitter. It works by narrowing the blood vessels.

When should Norepinephrine not be taken? (Contraindications)

Contraindicated to patients with history of high blood pressure, pregnancy, patients with peripheral or mesenteric vascular thrombosis (inflammation and injury of the small intestine result from inadequate blood supply), unless necessary as a life-saving procedure.

What is the dosage of Norepinephrine?

IV- The recommended initial dose is 8 to 12 mcg/min. Maximum allowed dose is 30mcg/min. The maintenance dose is 2 to 4 mcg/min.

How should Norepinephrine be taken?

Injection administered by a doctor or healthcare provider into the vein.

What are the warnings and precautions for Norepinephrine?

•Not a substitute for replacement of blood, plasma, fluids, and/or electrolytes; correct volume depletion (loss of both water and salts from cell volume) prior to admin.

Identify and correct hypoxia (reduced oxygen content), hypercapnia (too much of CO2and acidosis prior to or during admin.

Avoid extravasations (leakage of a fluid) as tissue necrosis may occur.

Avoid giving the injection into leg veins since they are more often affected by diseases such as diabetes and arteriosclerosis.

What are the side effects of Norepinephrine?

Heart- Fast/slow/irregular heartbeat, chest pain, low blood pressure.
Central Nervous System- Headache, dizziness, tremor, sleeplessness, anxiety, mental/mood changes.
Metabolic- Metabolic acidosis, increase in sugar level.
Respiratory- Breathing difficulties.
Miscellaneous- Necrosis (when infused into small vein), thyroid enlargement, irritation from extravasations, decreased urinary output.