Generic Name : Nitroxazepine Therapeutic Classification : Psychotherapeutics ICD Code : Y49.0
India- Sintamil. Why it is prescribed (Indications) :
This medication is a tricyclic antidepressant (TCA), prescribed for depression, and nocturnal enuresis. When it is not to be taken (Contraindications):
Dosage & When it is to be taken :
Adult- PO- The recommended dose is 25-50 mg at bedtime. How it should be taken :
It comes as a tablet to take by mouth, at bedtime. Warnings and Precautions :
* Caution should be exercised in patients with history of mental illness, any allergy, kidney or liver problems, diabetes, suicidal thoughts, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* It may cause drowsiness, dizziness, or blurred vision, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* Avoid exposure sunlight. Side Effects :
Heart - Low blood pressure, high blood pressure, fast heart rate, palpitations, heart attack, abnormal heart rhythm, heart block, ECG changes, and stroke.
Central Nervous System - Confusional states (especially in the elderly) with hallucinations, disorientation, delusions; anxiety, restlessness, agitation; sleeplessness and abnormal dreams, numbness, tingling, incoordination, ataxia, tremors, seizures, alterations in EEG patterns, and ringing in the ear.
Eye and ENT - Dry mouth, and, blurred vision, disturbances of accommodation and dilatation of pupil.
Allergic - Skin rash, petechiae, hives, itching, sensitivity to light, swelling in the eyes, face and tongue and drug fever.
Blood - Bone marrow depression including agranulocytosis and eosinophilia.
Gastrointestinal - Nausea and vomiting, loss of appetite, stomach distress, diarrhea, peculiar taste, mouth ulcer, abdominal cramps, black tongue, constipation, paralytic ileus.
Genitourinary - Breast enlargement in the male, spontaneous milk secretion in the female, increased or decreased sexual drive, impotence, testicular swelling, elevation or blood sugar level, urinary retention, delayed micturition and dilation of the urinary tract.
Miscellaneous - Jaundice, abnormal liver function, weight gain or loss, perspiration, flushing, urinary frequency, drowsiness, dizziness, weakness and fatigue, headache, parotid swelling, hair loss and proneness to falling.
* Avoid excess dosage. Storage Conditions :
Store the medication as directed by your physician.
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