Nisoldipine - Drug Information

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General Information on Nisoldipine

Generic Name : Nisoldipine

Pronunciation : nye-SOL-di-peen

Latest prescription information about Nisoldipine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y52.5 | Therapeutic Classification : Anti- Hypertensives

Trade Names/Brand Names of Nisoldipine

International- Sular.

Why is Nisoldipine Prescribed? (Indications)

This medication is a calcium channel blocker, prescribed for high blood pressure. It works by relaxing blood vessels.

When should Nisoldipine not to be taken? (Contraindications)

Hypersensitivity.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Nisoldipine?

Initial- The recommended dose is 20 mg orally once daily.

How should Nisoldipine be taken?

It comes as a tablet to take by mouth, on an empty stomach at least 1 hour before or 2 hours after eating.

What are the warnings and precautions for Nisoldipine?

Caution should be exercised in patients with history of chest pain, blood vessel disease, heart disease, liver impairment, low blood pressure, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding.
It may cause dizziness, drowsiness, or lightheadedness, do not drive a car or operate machinery while taking this medication.

What are the side effects of Nisoldipine?

   Body As A Whole : Skin infection, chills, facial edema, fever, flu syndrome and uneasiness.
   Heart : Atrial fibrillation, abnormal heart rhythm, heart failure, first degree AV block, high blood pressure, low blood pressure, migraine, heart attack.
   Gastrointestinal : Abnormal liver function tests, loss of appetite, intestinal inflammation, diarrhea, dry mouth, indigestion, difficulty in swallowing, flatulence, gastrointestinal bleeding, gum inflammation, tongue inflammation, liver enlargement, increased appetite, blood stool, mouth ulcer.
   Blood : Anemia, decrease in white blood cells.
   Metabolic : Gout, hypokalemia, increased serum creatine kinase, increased non-protein nitrogen, weight gain, weight loss and diabetes.
   Musculoskeletal : Joint pain, leg cramps, muscle pain, myasthenia, inflammation of skeletal muscles.
   Central Nervous System : Abnormal dreams, abnormal thinking and confusion, memory loss, anxiety, incoordination, stroke, decreased libido, depression, increased muscle tone, sleeplessness, nervousness, tingling, drowsiness, tremor, vertigo.
   Respiratory : Asthma, difficulty in breathing, wheezing, nosebleed, increased cough, inflammation of larynx, pharynx, lung infection.
   Skin : Pimples, hair loss, dry skin, fungal dermatitis, herpes simplex, herpes zoster, rash, itching, skin discoloration, skin ulcer, sweating, hives.
   Eye and ENT : Abnormal vision, eye inflammation, ear pain, increased eye pressure, itchy eyes, ear infection, retinal detachment, ringing in the ear, watery eyes, taste disturbances, temporary loss of vision.
   Genitourinary : Painful menstrual period, blood in urine, impotence, night time urination, urinary frequency, increased BUN and serum creatinine, vaginal bleeding, and vaginitis.

What are the other precautions for Nisoldipine?

Avoid excess dosage.

What are the storage conditions of Nisoldipine?

Store at 20-25C.

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