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Generic Name : Nifedipine
Pronunciation : nye fed' i peen
Trade Name(s):
India- Adalat oros, Adalat retard, Angiblock, Calbloc, Calbloc Retard, Calcigard, Cardipin, Cardules, Depicor, Depin, Myogard, Myogard-LA, Myogard-OD, Nicardia, Nicardia retard, Nifedine, Nifelat, Niferil, Novacard.
International- Adalat, Procardia, Afeditab, Nifediac.
Why it is prescribed (Indications) : This medication is a calcium channel blocker, prescribed for angina (chest pain), high blood pressure and abnormal heart rhythms.
When it is not to be taken (Contraindications): Contraindicated in patients with very low blood pressure or shock due to heart problems and hypersensitivity.
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
When it is to be taken : Adult: PO- The starting dose is one 10 mg 3 times/day. The usual effective dose range is 10-20 mg three times daily.
How it should be taken : It comes as a tablet and capsule to take by mouth, with or without food.
Special Instruction :
* Caution should be exercised in patients with history of chest pain, blood vessel problems, recent heart attack, irregular heartbeat; low blood pressure, liver or kidney disease, swelling in the extremities, fluid in lungs, any allergy, who are taking other medications, elderly, during pregnancy and breastfeeding.
* It may cause dizziness or lightheadedness, do not drive a car or operate machinery while taking this medication.
Side Effects :
Most Common -
Dizziness, lightheadedness, or faintness, headache, weakness, flushing, nausea, heartburn, muscle cramps, sore throat and swelling of feet or lower legs.
Heart -
Swelling in the extremities and palpitations.
Nausea, diarrhea, constipation, cramps and flatulence.
Respiratory -
Nasal and chest congestion and shortness of breath.
Musculoskeletal -
Inflammation, joint stiffness and muscle cramps.
Central Nervous System -
Shakiness, nervousness, jitteriness, sleep disturbances, blurred vision and difficulty in balance.
Miscellaneous -
Skin inflammation, itching, hives, fever, increased sweating, chills and sexual disorders.
Other Precautions :
* Avoid excess dosage.
Storage Conditions :
Store it at controlled room temperature (15° to 25°C).
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