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Nicardipine

Latest prescription information about Nicardipine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Nicardipine
Pronunciation : nya kar de peen
Therapeutic Classification : Anti- Hypertensives
ICD Code : Y52.5
Trade Name(s): 
International- Cardene, Cardene SR.
Why it is prescribed (Indications) : This medication is a calcium channel blocker, prescribed for high blood pressure and chest pain.  It works by relaxing blood vessels.
When it is not to be taken (Contraindications): Contraindicated in patients with advanced aortic stenosis.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : IV- Initiate therapy at 50 mL/hr (5.0 mg/hr).
How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with history of chest pain, heart failure, other heart problems, adrenal gland tumor, liver or kidney disease, low blood pressure, lung congestion, stroke, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
* It may cause dizziness or fainting, do not drive a car or operate machinery while taking this medication.
Side Effects : 
Most Common - Low blood pressure and fast heart rate.
Body as a Whole - Fever and neck pain.
Heart - Chest pain, block, ST segment depression, inverted T wave and deep-vein thrombophlebitis.
Gastrointestinal - Indigestion.
Blood - Reduced platelets count.
Metabolic - Decrease in blood minerals and swelling in extremities.
Central Nervous System - Confusion and increased muscle tone.
Respiratory - Respiratory disorder.
Eye and ENT - Eye inflammation, ear disorder and ringing in the ear.
Genitourinary - Urinary frequency.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at controlled room temperature (20° to 25°C).

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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