Medindia » Medication Manual » Nevirapine

Nevirapine

Latest prescription information about Nevirapine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Email Email print Print Save this page Save Syndicate Syndicate
Generic Name : Nevirapine
Pronunciation : ne- vye'- ra- peen
Therapeutic Classification : Antivirals
ICD Code : Y41.5
Trade Name(s): 
India- Nev Tab, Neve Tab, Nevimune Susp, Nevimune Tab, Nevipan Tab, Nevir Susp, Nevir Tab, Neviretro Tab.
International-Viramune.
Why it is prescribed (Indications) : This medication is a reverse transcriptase inhibitor, prescribed for HIV infection and AIDS. It inhibits the activity of reverse transcriptase enzyme and blocks the production of DNA and new viruses.  
When it is not to be taken (Contraindications): Hypersensitivity and in patients with severe liver impairment.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : Adult: PO- Combined with other antiretrovirals: The recommended dose is 200 mg once daily for the first 14 days; up to 200 mg twice daily if rash does not develop. Re-introduce at a lower dose for the first 14 days if the treatment is interrupted for >7 days.
How it should be taken : It comes as a tablet, to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of kidney disease, liver impairment, during pregnancy and breastfeeding.
* Patient may develop with increased risk of liver damage, serious life threatening allergic reactions, if it is so consult with your doctor.
* It may affect the effectiveness of oral contraceptives; consult with your doctor for other methods to prevent pregnancy while taking this medication.
* It may lead to redistribution/accumulation of body fat in many parts of body.
Side Effects : 
Body as whole- Swelling in the hand, feet, ankle and lower leg regions, fever and weight loss.
Skin- Rash
Gastrointestinal - Nausea, vomiting, diarrhea and abdominal pain.
Central Nervous System - Headache, fatigue, dizziness and depression.
Musculoskeletal - Muscle pain.
Respiratory - Dry cough.
Metabolic - Increase in liver enzymes.
Potentially Fatal: Severe and life-threatening liver toxicity and skin reactions.
Other Precautions : 
* It may reduce the effectiveness of contraceptives.
* Avoid alcoholic beverages.
Storage Conditions : 
Oral: Store it at 15-30°C, and in an airtight container, keep away from children and light.

Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.

Browse the Drugs alphabetically

Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
Drugs Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z