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Nadolol

Latest prescription information about Nadolol. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Nadolol
Pronunciation : nay doe' lole
Therapeutic Classification : Beta- Adrenergic Blockers
ICD Code : Y51.7
Trade Name(s): 
International- Corgard.
Why it is prescribed (Indications) : This medication is a beta-adrenergic receptor blocker, prescribed for high blood pressure and chest pain. It slows down the heart's pumping speed.
When it is not to be taken (Contraindications): Contraindicated in patients with asthma, severe heart diseases such as sinus bradycardia, cardiogenic shock, and overt cardiac failure and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : PO- The recommended dose is 40-320 mg once daily. The maximum dose for treating angina is 240 mg daily and for hypertension is 320 mg daily.
How it should be taken : It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of breathing problems, sugar, heart failure, overactive thyroid, kidney, poor blood circulation, tumor, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.
* Avoid abrupt withdrawal.
* It may affect blood sugar level, monitor sugar level regularly while taking this medication.
* Monitor liver and heart functions regularly while taking this medication.
Side Effects : 
Heart - Slow heart rate, heart failure, low blood pressure and abnormal heart rhythm.
Central Nervous System - Dizziness, fatigue, tingling, sleepiness and change in behavior.
Respiratory - Asthma.
Gastrointestinal - Nausea, diarrhea, abdominal discomfort, constipation, vomiting, indigestion, loss of appetite, bloating, and flatulence.
Miscellaneous - Rash, itching, headache, dry mouth, eyes or skin, impotence, facial swelling, weight gain, slurred speech, cough, increased sweating, ringing in the ear and blurred vision.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature and away from light.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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