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Generic Name : Nabumetone
Pronunciation : nab-UE-me-tone
Therapeutic Classification : analgesics
Trade Name(s):
India- Nabuflam Tab , Nilitis Tab , Niltis Tab. International- Relafen. This medication is a nonsteroidal anti-inflammatory agent(NSAIA), used to treat pain and inflammation associated with muscle, bone and joint disorders such as rheumatoid arthritis and osteoarthritis. When it is not to be taken (Contraindications):
When it is to be taken : Adult: Oral- 1 g as a single dose in the evening, followed by 0.5-1 g in the morning if needed. How it should be taken : It comes as a tablet to take by mouth, with or without food. Special Instruction : *Caution should be exercised in patients with history of pre-existing cardiovascular risk factors or disease; fluid retention, high blood pressure, digestive tract ulcers, elderly or debilitated patients, other forms of asthma, liver disease. * It could cause heart attack and stroke especially in patients already at a risk. *Closely monitor patients with any abnormal liver function test, and kidney disease. Withhold for at least 4-6 half-lives prior to surgical or dental procedures. Side Effects : Most Common- Diarrhea, dyspepsia, and abdominal pain. Gastrointestinal- Gastritis, gastrointestinal ulcers and bleeding, Constipation, flatulence, nausea, , dry mouth, difficulty in swallowing , mouth ulcer, vomiting, altered appetite, liver function abnormalities including liver failure. Central Nervous System- Dizziness, headache, fatigue, increased sweating, sleeplessness, nervousness, drowsiness, weakness, agitation, anxiety, confusion, depression, tingling, tremor, fainting. Skin- Mild to severe allergic reactions, increased sensitivity to light. Heart- Inflammation of blood vessels. It could increase the incidence of heart attack and stroke. Respiratory- Difficulty in breathing, lung inflammation. Genitourinary- Decrease in kidney function, , kidney failure, vaginal bleeding. Eye and ENT- Ringing in the ear, abnormal vision. Blood- Decrease in platelets. Metabolic- Weight gain. Miscellaneous- Swelling of the leg. Hypersensitivity- Serious allergic reactions which lead to death. *Do not take aspirin while using this medication. Storage Conditions : Oral: Store it at room temperature (20-25°C). Store it in an airtight container, and keep away from children. |
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