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Modafinil

Latest prescription information about Modafinil. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Modafinil
Pronunciation : Mode-uh-fin-il
Therapeutic Classification : Analeptics
ICD Code : Y50.0
Trade Name(s): 
India- Modalert, Modapro, Modfil, Provake.
International- Provigil, Alertec, Modavigil, Modalert, Modiodal, Modafinilo, Carim, Vigia.
Why it is prescribed (Indications) : This medication is an analeptic drug, prescribed for narcolepsy, obstructive sleep apnea and shift work disorder.  It works by altering neurotransmitters in the brain.
When it is not to be taken (Contraindications): Hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : PO- The usual dose is 200-400mg daily as a single morning dose or in 2 divided doses.
How it should be taken : It is available as tablets to take by mouth at bed time.
Warnings and Precautions : 
* Caution should be exercised in patients with history of heart, liver, kidney disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.
*It may cause dizziness or blurred vision, do not drive a car or operate machinery.
*Avoid alcohol consumption.
*Rarely patient may develop with increased risk of skin reactions (eg, Stevens-Johnson syndrome, toxic epidermal necrolysis)with the following symptoms: red, swollen, blistered, or peeling skin; or blisters on the inside of the eyes, nose, or mouth.If it is so consult with your doctor.
Side Effects : 
Sleeplessness, nervousness, aggression, headache, loss of appetite, gastrointestinal disturbances, palpitations and rash.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature (15-30°C).

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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