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Mitoxantrone

Latest prescription information about Mitoxantrone. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Mitoxantrone
Pronunciation : mye-toe-ZAN-trone
Therapeutic Classification : Chemotherapy
Trade Name(s): 
India- Mitozan Vial, Oncotron Vial.
International-Novantrone.
Why it is prescribed (Indications) : This medication is an antineoplastic agent, prescribed for metastatic breast cancer, acute myeloid leukemia, non-Hodgkin's lymphoma, and acute lymphoblastic leukaemia.

When it is not to be taken (Contraindications): 

Hypersensitivity.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : Adult- IV- The recommended dose is 10-12 mg/m2.
How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the vein.
Special Instruction : 
* Caution should be exercised in patients with history of chickenpox, herpes, bone marrow depression, liver problems, heart problems, gout, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* Avoid contact with people who have infections.
* It may reduce platelet counts; avoid bruising and injury.
* Monitor complete blood cell counts, liver function tests, blood chemistry, pregnancy tests, uric acid levels, and heart function regularly while taking this medication.
* It should not be used in children.
Side Effects : 
Most Common - Nausea, hair loss, menstrual disorder, absence of menstrual period, upper respiratory tract infection, urinary tract infection, mouth ulcer, abnormal heart rhythm, diarrhea, ECG abnormal, constipation, back pain and headache.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at controlled room temperature (15°-25°C).

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