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Mitotane - Indications, Dosage, Side Effects and Precautions

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Information about Mitotane

Generic Name : Mitotane
Up-to-date prescription details regarding Mitotane are provided here.

Pronunciation : mye' toe tane

Learn the correct pronunciation of the Mitotane, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


Trade Names/Brand Names of Mitotane

International :


Lysodren

Why is Mitotane Prescribed? (Indications)

This medication is an anti-cancer agent, prescribed for adrenal cortical cancer which is not treated with surgery. It slows growth or reduces the size of the tumor.

What is the dosage of Mitotane?

Initially 2 to 6 g/day orally in divided doses, 3 or 4 times daily. Increase it up to 9 to 10 g/day. The maximum dose is 16 g/day.

How should Mitotane be taken?

It comes as a tablet to take by mouth (orally). It is usually taken three to four times a day with or without food.

What are the warnings and precautions for Mitotane?

•It may cause drowsiness or dizziness. Do not drive a car or operate machinery while taking this medication.

Monitor adrenal functions, neurological and behavioral signs.

Avoid using in children.

What are the side effects of Mitotane?

Heart- Hypertension, sudden fall in blood pressure, flushing.
Central Nervous System- Lethargy, drowsiness, dizziness, vertigo.
Skin- Skin toxicity.
Eye- Non-inflammatory disease of the retina, visual blurring, double vision.
Gastrointestinal-Loss of appetite, nausea, vomiting, diarrhea.
Genitourinary- Blood in urine, inflammation of the bladder, albumin is present in the urine.
Miscellaneous- Generalized aching, extreme elevation of body temperature.

What are the other precautions for Mitotane?

After trauma or severe shock, stop the medication.

What are the storage conditions for Mitotane?

Store at 77 degrees F (25 degrees C). Store it in an airtight container and keep away from children.
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