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Generic Name : Mitotane
Pronunciation : mye' toe tane
Therapeutic Classification : Chemotherapy
Trade Name(s):
International- Lysodren. This medication is an anti-cancer agent, prescribed for adrenal cortical cancer which is not treated with surgery. It slows growth or reduces the size of the tumor.
When it is to be taken : Initially 2 to 6 g/day orally in divided doses, 3 or 4 times daily. Increase it up to 9 to 10 g/day. The maximum dose is 16 g/day. How it should be taken : It comes as a tablet to take by mouth (orally). It is usually taken three to four times a day with or without food. Special Instruction : *It may cause drowsiness or dizziness. Do not drive a car or operate machinery while taking this medication. *Monitor adrenal functions, neurological and behavioral signs. *Avoid using in children. Side Effects : Heart- Hypertension, sudden fall in blood pressure, flushing. Central Nervous System- Lethargy, drowsiness, dizziness, vertigo. Skin- Skin toxicity. Eye- Non-inflammatory disease of the retina, visual blurring, double vision. Gastrointestinal-Loss of appetite, nausea, vomiting, diarrhea. Genitourinary- Blood in urine, inflammation of the bladder, albumin is present in the urine. Miscellaneous- Generalized aching, extreme elevation of body temperature. *After trauma or severe shock, stop the medication. Storage Conditions : Store at 77 degrees F (25 degrees C). Store it in an airtight container and keep away from children. |
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