This medication is a chemotherapy agent, prescribed for adenocarcinoma (cancer of the stomach or pancreas) either alone or with other medications. It blocks cancer cell growth.
Contraindicated in patients with bleeding disorder due to low platelet counts and hypersensitivity.
IV- The recommended initial dose is 10 to 20 mg/m2, every 6 to 8 weeks.
It comes as a solution for injection, to be administered by a healthcare provider into the vein.
• Caution should be exercised in patients with history of kidney, breathing, bone marrow problems, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
• It may reduce platelet counts, which lead to severe bleeding; avoid injury or bruising.
• Avoid contact with people who have infections.
• Avoid vaccination during the treatment period.
• Monitor complete blood cell count, and kidney function regularly while taking this medication.
• Severe effects :
Bone marrow depression, heart failure, liver and kidney damage, abnormal decrease in platelet counts.
• Gastrointestinal : Nausea, vomiting, anorexia, and mouth ulcer.
• Skin : Hair loss, nail discoloration, rash and itching.
• Respiratory : Lung infection/inflammation, cough and difficulty in breathing.
• Miscellaneous : Fever, tingling, elevated liver enzyme, uneasiness and bladder fibrosis/contraction.
Avoid excess dosage.
Normally handled and stored by healthcare providers.
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