Generic Name : Mitomycin Pronunciation : mye toe mye' sin
Therapeutic Classification : Chemotherapy Trade Name(s):
India- Almito, Mitocin, Mitodus, Mitomycin, Mitonco, Oncocin.
International- Mutamycin. Why it is prescribed (Indications) : This medication is a chemotherapy agent, prescribed for adenocarcinoma (cancer of the stomach or pancreas) either alone or with other medications. It blocks cancer cell growth. When it is not to be taken (Contraindications): Contraindicated in patients with bleeding disorder due to low platelet counts and hypersensitivity.
Dosage & When it is to be taken : IV- The recommended initial dose is 10 to 20 mg/m2, every 6 to 8 weeks. How it should be taken : It comes as a solution for injection, to be administered by a healthcare provider into the vein. Warnings and Precautions :
* Caution should be exercised in patients with history of kidney, breathing, bone marrow problems, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
* It may reduce platelet counts, which lead to severe bleeding; avoid injury or bruising.
* Avoid contact with people who have infections.
* Avoid vaccination during the treatment period.
* Monitor complete blood cell count, and kidney function regularly while taking this medication. Side Effects :
Severe effects - Bone marrow depression, heart failure, liver and kidney damage, abnormal decrease in platelet counts.
Gastrointestinal - Nausea, vomiting, anorexia, and mouth ulcer.
Skin - Hair loss, nail discoloration, rash and itching.
Respiratory - Lung infection/inflammation, cough and difficulty in breathing.
Miscellaneous - Fever, tingling, elevated liver enzyme, uneasiness and bladder fibrosis/contraction.
* Avoid excess dosage. Storage Conditions :
Normally handled and stored by healthcare providers.
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