Mitomycin - Drug Information

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General Information on Mitomycin

Generic Name : Mitomycin

Pronunciation : mye toe mye' sin

Latest prescription information about Mitomycin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Why is Mitomycin Prescribed? (Indications)

This medication is a chemotherapy agent, prescribed for adenocarcinoma (cancer of the stomach or pancreas) either alone or with other medications.  It blocks cancer cell growth.

When should Mitomycin not to be taken? (Contraindications)

Contraindicated in patients with bleeding disorder due to low platelet counts and hypersensitivity.

Pregnancy Category

A B C D X

Category D :

There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.

What is the dosage of Mitomycin?

IV- The recommended initial dose is 10 to 20 mg/m2, every 6 to 8 weeks.

How should Mitomycin be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Mitomycin?

• Caution should be exercised in patients with history of kidney, breathing, bone marrow problems, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
• It may reduce platelet counts, which lead to severe bleeding; avoid injury or bruising.
• Avoid contact with people who have infections.
• Avoid vaccination during the treatment period.
• Monitor complete blood cell count, and kidney function regularly while taking this medication.

What are the side effects of Mitomycin?

   Severe effects : Bone marrow depression, heart failure, liver and kidney damage, abnormal decrease in platelet counts.
   Gastrointestinal : Nausea, vomiting, anorexia, and mouth ulcer.
   Skin : Hair loss, nail discoloration, rash and itching.
   Respiratory : Lung infection/inflammation, cough and difficulty in breathing.
   Miscellaneous : Fever, tingling, elevated liver enzyme, uneasiness and bladder fibrosis/contraction.

What are the other precautions for Mitomycin?

Avoid excess dosage.

What are the storage conditions of Mitomycin?

Normally handled and stored by healthcare providers.

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