Medindia » Medication Manual » Mitomycin

Mitomycin

Latest prescription information about Mitomycin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Email Email print Print Save this page Save Syndicate Syndicate
Generic Name : Mitomycin
Pronunciation : mye toe mye' sin
Therapeutic Classification : Chemotherapy
Trade Name(s): 
India- Almito, Mitocin, Mitodus, Mitomycin, Mitonco, Oncocin.
International- Mutamycin.
Why it is prescribed (Indications) : This medication is a chemotherapy agent, prescribed for adenocarcinoma (cancer of the stomach or pancreas) either alone or with other medications.  It blocks cancer cell growth.
When it is not to be taken (Contraindications): Contraindicated in patients with bleeding disorder due to low platelet counts and hypersensitivity.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : IV- The recommended initial dose is 10 to 20 mg/m2, every 6 to 8 weeks.
How it should be taken : It comes as a solution for injection, to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with history of kidney, breathing, bone marrow problems, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
* It may reduce platelet counts, which lead to severe bleeding; avoid injury or bruising.
* Avoid contact with people who have infections.
* Avoid vaccination during the treatment period.
* Monitor complete blood cell count, and kidney function regularly while taking this medication.
Side Effects : 
Severe effects - Bone marrow depression, heart failure, liver and kidney damage, abnormal decrease in platelet counts.
Gastrointestinal - Nausea, vomiting, anorexia, and mouth ulcer.
Skin - Hair loss, nail discoloration, rash and itching.
Respiratory - Lung infection/inflammation, cough and difficulty in breathing.
Miscellaneous - Fever, tingling, elevated liver enzyme, uneasiness and bladder fibrosis/contraction.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Normally handled and stored by healthcare providers.

Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.

Browse the Drugs alphabetically

Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
Drugs Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z