Medindia » Medication Manual » Mifepristone

Mifepristone

Latest prescription information about Mifepristone. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Email Email print Print Save this page Save Syndicate Syndicate
Generic Name : Mifepristone
Pronunciation : MIF-eh-pri-stone
Therapeutic Classification : Antiprogesterone
Trade Name(s): 
India- Abo Pill Tab, Abortom Kit, Cedate Tab, Colestone, Elmif Tab, M .F.T., O Pill, Mefipil Tab, Mifebort Syr, Mifebort Tab, Mifegest Tab, Mifeprin Tab, Miferiv Tab, Mistone Tab, Mtpill Tab, No Chance, Relezed Tab, Termipil Tab, T-Pill + Miso Tab, Undo Tab, Unwanted Tab.
International-Mifeprex.
Why it is prescribed (Indications) : 
This medication is a synthetic steroid, used alone or together with another medication, to end an early pregnancy (within 7 weeks of the start of a woman's last menstrual period). It blocks the hormone needed for pregnancy to continue. It is also indicated for high blood sugar levels (hyperglycemia) in adults with endogenous Cushing’s syndrome.  
When it is not to be taken (Contraindications): 
Contraindicated in patients with confirmed or suspected fertilized egg has implanted outside the uterus, chronic adrenal failure, concurrent long-term corticosteroid therapy, history of allergy to mifepristone, misoprostol or other prostaglandin, bleeding disorders, liver or kidney impairment; pregnancy and lactation; IUD in place; undiagnosed uterus mass.

Pregnancy Category :

A B C D X
Category X : Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Dosage & When it is to be taken : 
Oral- Termination of pregnancy (49 days or less duration)- Adult: 600 mg as a single dose followed 2 days later by 400 mcg of misoprostol as single dose.
How it should be taken : 
This medication available in the form of tablet to take by mouth with or without food, only under healthcare provider’s supervision. First time 2 tablets, if it doesn't work.
Warnings and Precautions : 
*Do not use this if your pregnancy is outside the womb (ectopic pregnancy). It will not cause an abortion in this case.
*It may cause dizziness. Do not drives, operate machinery, or do anything while taking this medication.
*It should be used with caution in patients with kidney, heart, lung, liver, adrenal disease. Patients with diabetes, high blood pressure and porphyria should also inform their doctor about their illness prior to taking this medication.
Side Effects : 
Genitourinary- Excessive vaginal bleeding, uterus infections, uterus bleeding, urinary tract infection.
Gastrointestinal- Diarrhea, nausea, vomiting, stomach cramps.
Central Nervous System- Dizziness, headache, anxiety, fatigue, unusual tiredness or weakness.
Metabolic- Swelling in the extremities and decreased appetite.
Musculoskeletal- Joint pain.
Miscellaneous- Back pain, fever.
Other Precautions : 
*Avoid smoking, alcohol consumption.
Storage Conditions : 
Normally handled and stored by healthcare providers.

Related News

Mifepristone Reliable For Treating Uterine Fibroids

According to a study conducted by University of Rochester, Low doses of the drug mifepristone (also known as RU-486) shrinks the uterine fibroid tumors and greatly improves the quality of life in ...
Sepsis Death Reported With Mifepristone - FDA Issues Warning

Last Tuesday the FDA issued a public health advisory, warning physicians to watch for any signs of sepsis or other infection among women who have taken Danco Laboratories' Mifeprex -- known ...

Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.
Posted by:  raj.0807, India  Posted on: 4/10/2013
My Girl Friend is of 18year and i think she is preganent so what sort of dosage she must have please its urgent?
Posted by:  lathashree, India  Posted on: 2/16/2013
I have 2 girl babies one of 9 yrs and one of 4 yrs and i have 5 weeks pregnancy. and i dont want 3rd baby. what pills should i use to destroy pregnancy. please sugest me as early as possible.
Posted by:  english, India  Posted on: 1/24/2013
if both dosages can be taken of same mg than whethere it should be effected or not?
Posted by:  mahi_pharmacist, India  Posted on: 10/23/2012
i have taken mefiprin 3 divided doses of single dose i dint get vaginal bleeding whats the problem
Posted by:  bijon, India  Posted on: 4/6/2012
I used Mifeprin first dose on 5th april and second on 7 th April.But there is not starting bleeding.What is the reason for it?
View All Comments (6)

Browse the Drugs alphabetically

Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
Drugs Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z