Mifepristone - Drug Information

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Generic Name : Mifepristone

Pronunciation : MIF-eh-pri-stone

Latest prescription information about Mifepristone. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Antiprogesterone

Trade Names/Brand Names : 

India : 

International : 

Mifeprex

Why it is prescribed : 

This medication is a synthetic steroid, used alone or together with another medication, to end an early pregnancy (within 7 weeks of the start of a woman's last menstrual period). It blocks the hormone needed for pregnancy to continue. It is also indicated for high blood sugar levels (hyperglycemia) in adults with endogenous Cushing’s syndrome.  

When it is not to be taken (Contraindications): 

Contraindicated in patients with confirmed or suspected fertilized egg has implanted outside the uterus, chronic adrenal failure, concurrent long-term corticosteroid therapy, history of allergy to mifepristone, misoprostol or other prostaglandin, bleeding disorders, liver or kidney impairment; pregnancy and lactation; IUD in place; undiagnosed uterus mass.

Pregnancy Category :


A B C D X

Category X :

Animal and/or human studies have demonstrated fetal injury and potential risks outweigh the benefits of the drug in pregnancy. These drugs are found to be harmful when taken during pregnancy, and should not be used.

Dosage & When it is to be taken (Indications): 

Oral- Termination of pregnancy (49 days or less duration)- Adult: 600 mg as a single dose followed 2 days later by 400 mcg of misoprostol as single dose.

How it should be taken : 

This medication available in the form of tablet to take by mouth with or without food, only under healthcare provider’s supervision. First time 2 tablets, if it doesn't work.

Warnings and Precautions : 

•Do not use this if your pregnancy is outside the womb (ectopic pregnancy). It will not cause an abortion in this case.
• It may cause dizziness. Do not drives, operate machinery, or do anything while taking this medication.
•It should be used with caution in patients with kidney, heart, lung, liver, adrenal disease. Patients with diabetes, high blood pressure and porphyria should also inform their doctor about their illness prior to taking this medication.

Side Effects : 

  Genitourinary: Excessive vaginal bleeding, uterus infections, uterus bleeding, urinary tract infection.
  Gastrointestinal: Diarrhea, nausea, vomiting, stomach cramps.
  Central Nervous System: Dizziness, headache, anxiety, fatigue, unusual tiredness or weakness.
  Metabolic: Swelling in the extremities and decreased appetite.
  Musculoskeletal: Joint pain.
  Miscellaneous: Back pain, fever.

Other Precautions : 

Avoid smoking, alcohol consumption.

Storage Conditions : 

Normally handled and stored by healthcare providers.


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marlene765 

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RobertArmstrong 

Nice post. Mifepristone is best medicine used to terminate unwanted pregnancy up to 7 weeks.

lisa6y 

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SNTalukdar 

I m 40 days pregnant and wan to use Mifepriston, will it work?

daynighthealthcare 

Mifepristone is anti androgenic pill effective in termination of fetus by disintegrations of growing womb. 200mg of single dose are effective within 4 weeks of termination.

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