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Mifamurtide - Indications, Dosage, Side Effects and Precautions

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Information about Mifamurtide

Generic Name : Mifamurtide
Up-to-date prescription details regarding Mifamurtide are provided here.

Understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


Therapeutic Classification : Immunomodulators

Trade Names/Brand Names of Mifamurtide

International :


Mepact

Why is Mifamurtide Prescribed? (Indications)

This medication is an immunomodulator, prescribed for osteosarcoma (a kind of bone cancer) along with other chemotherapy agents. It was designated as an ‘orphan medicine’ (a drug used for rare disease condition).

When should Mifamurtide not be taken? (Contraindications)

It should not be co-administered with calcineurin inhibitors, high-dose non-steroidal anti-inflammatory drugs (NSAIDs). Contraindicated in patients with known hypersensitivity.

What is the dosage of Mifamurtide?

The dose is based on patient’s height and weight. The recommended dose is 2 mg/m2 body surface area.

How should Mifamurtide be taken?

It comes as a powder (diluted with fluid) for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Mifamurtide?

• Caution should be exercised in patients with liver or kidney impairment, respiratory distress, decrease in blood cells, heart disease, elderly, during pregnancy and breastfeeding.

• It is not recommended for use in children below the age of 2.

• It may cause dizziness or blurred vision, do not drive a car or operate machinery while taking this medication.

What are the side effects of Mifamurtide?

Blood - Anemia.
Metabolic - Loss of appetite.
Central Nervous System - Headache and dizziness.
Eye and ENT - Hearing loss.
Heart - Fast heart rate high blood pressure, and low blood pressure.
Respiratory - Difficulty in breathing, cough, and rapid breathing.
Gastrointestinal - Nausea, vomiting, constipation, diarrhea and abdominal pain.
Skin - Excessive sweating.
Musculoskeletal- Muscle pain, back pain, extremity pain and joint pain.
General - Chills, fever, fatigue, uneasiness, weakness, fluid retention, chest pain, Increase in blood urea and blood creatinine.

What are the other precautions for Mifamurtide?

Avoid excess dosage.

What are the storage conditions for Mifamurtide?

Store in a refrigerator (2°C – 8°C). Do not freeze. Keep the vial in the outer carton in order to protect from light.
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