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Midazolam

Latest prescription information about Midazolam. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Midazolam
Pronunciation : med-ZOOL-ham
Therapeutic Classification : Sedative-hypnotic Drugs
ICD Code : Y47.1
Trade Name(s): 
India- Benzosed, Fulsed, Insed, Mezolam, Miben, Midapic, Midaz, Midosed, Midzee, Midzol, Sedeven, Sedoz, Shortal, Verzol, Midclam.
International- Versed.
Why it is prescribed (Indications) : This medication is a benzodiazepine, prescribed for preoperative sedation, anxiolysis and amnesia.  It works by slowing activity in the brain to allow relaxation and sleep.
When it is not to be taken (Contraindications): Contraindicated in patients with increased eye pressure, alcohol intoxication, who are taking protease inhibiter, and hypersensitivity.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : Preoperative- Adult- IM - The recommended dose is 0.07 to 0.08 mg/kg administered up to 1 hour before surgery.
IV- Initial: 1 to 2.5 mg given 5-10 minutes before procedure. Repeat after at least 2 mins if needed.
How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the vein or large muscle.
Warnings and Precautions : 
* Caution should be exercised in patients with history of breathing problem (COPD); increased eye pressure, heart, liver, or kidney problems, porphyria, severe depression, drug dependence, alcoholism, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
Side Effects : 
Serious effects - Decreased tidal volume and respiration rate.
Gastrointestinal - Nausea, increased appetite and vomiting.
Central nervous System - Reduced alertness, confusion, emotion, hallucinations, fatigue, dizziness, incorodination, post-operative sedation and memory loss.
Miscellaneous - Jaundice, irregular heartbeat, shock, headache and cough.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature (25°C).

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Member Comments ( 1 )
do u send midazolam to singapore? what is the price?
(Posted by viv.., Singapore Date : 6/11/2012 )

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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