Generic Name : Midazolam Pronunciation : med-ZOOL-ham Therapeutic Classification : Sedative-hypnotic Drugs ICD Code : Y47.1
India- Benzosed, Fulsed, Insed, Mezolam, Miben, Midapic, Midaz, Midosed, Midzee, Midzol, Sedeven, Sedoz, Shortal, Verzol, Midclam.
International- Versed. Why it is prescribed (Indications) : This medication is a benzodiazepine, prescribed for preoperative sedation, anxiolysis and amnesia. It works by slowing activity in the brain to allow relaxation and sleep. When it is not to be taken (Contraindications): Contraindicated in patients with increased eye pressure, alcohol intoxication, who are taking protease inhibiter, and hypersensitivity.
Dosage & When it is to be taken : Preoperative- Adult- IM - The recommended dose is 0.07 to 0.08 mg/kg administered up to 1 hour before surgery.
IV- Initial: 1 to 2.5 mg given 5-10 minutes before procedure. Repeat after at least 2 mins if needed. How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the vein or large muscle. Warnings and Precautions :
* Caution should be exercised in patients with history of breathing problem (COPD); increased eye pressure, heart, liver, or kidney problems, porphyria, severe depression, drug dependence, alcoholism, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption. Side Effects :
Serious effects - Decreased tidal volume and respiration rate.
Gastrointestinal - Nausea, increased appetite and vomiting.
Central nervous System - Reduced alertness, confusion, emotion, hallucinations, fatigue, dizziness, incorodination, post-operative sedation and memory loss.
Miscellaneous - Jaundice, irregular heartbeat, shock, headache and cough.
* Avoid excess dosage. Storage Conditions :
Store it at room temperature (25°C).
Comment & Contribute
Ask an Expert