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Metronidazole

Latest prescription information about Metronidazole. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Metronidazole
Pronunciation : me, troe, ni', da, zole
Therapeutic Classification : Miscellaneous Anti- Infectives
ICD Code : Y41
Trade Name(s): 
India- Abdogyl-N, Aldezole, Aldiagram, Aldiamycin, Amibex, Amibex-Na, Anaerid-S, Antamebin, Aristogyl, Atodine-M, Avimet Sus, Bactomet, Bactomet-C, Balgyl Gel, C-Flox-M, Compeba, Darmed, Diarlop Pl, Drez-V, Ecoseptic, E-Dine-M, Entakon-M, Entrozyme, Flagyl, Floxzen-M, Glucogyl, Gramogyl, Gramoneg-M, Intagyl, Ivmetro, Lupigyl Ge, Matrix-Mn, Medilop, Meklin, Melam Gel, Met, Metgyl, Metris, Metro Gel, Metro Plus, Metrogyl, Metrogyl G, Metrogyl-P, Metrohex, Metrokind, Metron, Metron I.V, Metronidaz, Metronidaz, Metronidaz, Metro-P, Mezodin, Mlc , Monizole, Nalidys, Negadix-M, Obit-M Sus, Okaflox-M, Olife-M, Orahex-M, Orex-M, Orex-M Gel, Pdzole-D, Pomen, Pometal, Port-M, Povate, Sayodine-M, Sprot-P, Stedmox-M, Vardine-M, Zoacide, Zotadine-M.
International- Metronidazole Oral, MetroGel Vaginal, Vandazole, MetroLotion.
Why it is prescribed (Indications) : This medication is an antibacterial agent, prescribed for trichomoniasis, amebiasis and other bacterial infections.  It fights against bacteria in the body.
When it is not to be taken (Contraindications): Hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : PO- One-day treatment - two grams of flagyl, given either as a single dose or in two divided doses of one gram each given in the same day.
Seven-day course of treatment�250 mg three times daily for seven consecutive days.
Vaginal Gel- one applicator is administered intravaginally once a day for 5 days.
How it should be taken :  It comes as a tablet to take by mouth, with or without food. It also comes as vaginal gel, to be introduced into the vagina.
Warnings and Precautions : 
* Caution should be exercised in patients with history of nerve, brain, Crohn�s disease, liver impairment, seizures, heart disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* Avoid long-term use of this medication; otherwise it may cause secondary infection.
Side Effects : 
Most common - Headache, loss of appetite, vomiting, diarrhea and abdominal cramping.
Blood - Decrease in white blood cells and platelets.
Heart - ECG changes.
Central Nervous System - Brain disease, seizures, eye nerve problems, dizziness, unsteadiness, in coordination, confusion, irritability, depression, weakness and sleeplessness.
Hypersensitivity - Hives, rash, Stevens-Johnson syndrome, skin death, flushing, nasal congestion, dryness of the mouth and fever.
Genitourinary - Painful urination, bladder inflammation, adequate urination and incontinence.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store this medication at room temperature, out of reach of children.

Related News

Metronidazole Increases Risk Of Premature Deliveries.

In Britain a study was conducted on the usefulness of the antibiotic metronidazole. This is because in England around 42,500 babies are born before their full term (22-36 weeks). Western Europe has ...

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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