Metolazone - Drug InformationGeneric Name : Metolazone | Pronunciation : me tole' a zone
Why it is prescribed (Indications) :This medication is a quinazoline diuretic, prescribed for high blood pressure. It helps the kidneys to ged rid of unwanted water and salt from the body into the urine.
When it is not to be taken (Contraindications):Contraindicated in patients with anuria (absence of urination), liver damage, and hypersensitivity.
Pregnancy Category :
Category D :There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Dosage & When it is to be taken :PO- Adults- The recommended dose range is 2.5 – 10 mg/day.
How it should be taken :It comes as a tablet to take by mouth, with food.
Warnings and Precautions :Caution should be exercised in patients with history of lupus, kidney or liver disease, low blood mineral levels, gout, any allergy, who are taking other medications, during pregnancy and breastfeeding.
It may cause drowsiness, dizziness, blurred vision or lightheadedness, do not drive a car or operate machinery while taking this medication.
Avoid alcohol consumption.
Avoid exposure to sunlight.
Monitor liver function, kidney function, and complete blood cell counts regularly while taking this medication.
Side Effects :
Heart - Cold extremities, swelling, low blood pressure and palpitations.
Central Nervous System - Anxiety, depression, dry mouth, impotence, nervousness, weakness and “weird” feeling.
Skin - Itching, rash and skin dryness.
Eyes, Ears, Nose, Throat - Cough, nose bleed, eye itching, sinus congestion, sore throat and ringing in the ears.
Gastrointestinal - Abdominal discomfort (pain, bloating), bitter taste, constipation, diarrhea, nausea and vomiting.
Genitourinary - Night-time urination.
Musculoskeletal - Back pain.