Medindia » Medication Manual » Metoclopramide

Metoclopramide

Latest prescription information about Metoclopramide. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Email Email print Print Save this page Save Syndicate Syndicate
Generic Name : Metoclopramide
Pronunciation : MET-oh-KLOE-pra-mide
Therapeutic Classification : Antiemetics
ICD Code : Y43.0
Trade Name(s): 
India- Bacnorm Drops, Donmet Inj, Emenil Inj, Emenil Tab, Emenorm Inj, Emenorm Tab, Labmet Amp, Maxeron Inj, Maxeron Syr, Maxeron Tab, Maxinorm Tab, Metadrate Susp, Metadrate Tab, Metajex Inj, Metarmin Inj Inj, Metoclop Amp, Metoclop Vial, Nausifar Mps Gel, Nausifar Mps Tab, Periglo Amp, Perinorm Dispertab, Perinorm Inj, Perinorm Syr, Perinorm Tab, Perinorm-Cd Cap, Promet Inj, Reggi Syr, Reggi Tab, Reglan Inj, Reglan Syr, Reglan Tab, Reglan Vial, Rivnorm Tab, Sianorm Inj, Sigmet Inj, Tomid Syr, Tomid Tab, Vominorm Inj, Vominorm Tab.
International- Reglan , Metozolv ODT.
Why it is prescribed (Indications) : 
This medication is a gastrointestinal stimulant and antinauseant, prescribed for heartburn and esophagitis due to GERD and for treating patients who have gastroparesis (partial paralysis of the stomach) and prevention of nausea and vomiting associated with cancer chemotherapy. 
When it is not to be taken (Contraindications): 
Contraindicated in patients with pheochromocytoma, bleeding, blockage, or perforation in stomach or intestines; and hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : 
Gastroparesis is treated with 10 mg administered orally four times daily, 30 minutes before each meal and at bedtime.
Nausea and vomiting associated with emetogenic cancer chemotherapy:
Adults: IV- 2 mg/kg by infusion 30 min before chemotherapy, repeated every 2 hours for 2 doses, then every 3 hours for 3 doses.
How it should be taken : 
It comes as a tablet, an orally disintegrating (dissolving) tablet, and a solution (liquid) to take by mouth. It is usually taken 4 times a day on an empty stomach, 30 minutes before each meal and at bedtime. Injection is administered by health care providers into the vein.
Warnings and Precautions : 
*Caution needed for children, elderly, patients with history of liver or kidney disease, porphyria (group of inherited or acquired disorders of certain enzymes), epilepsy, Parkinson's disease, diabetes, history of depression.
*It may cause dizziness. Do not drive a car or operate machinery until you know how this medication affects you.
*Do not drink alcohol or use medicines that may cause drowsiness.
*Do not take more than the recommended dose or use this medication for longer than 12 weeks without checking with your doctor.
*Avoid prolong usage of this medication, otherwise it may lead to involuntary movements.
Side Effects : 
Heart- Acute heart failure, slow heart rate, fluid retention, high blood pressure, low blood pressure and fast heart rate.
Central Nervous System- Sedation, dizziness, restlessness, involuntary body movements, spasms, depression, malignant neuroleptic syndrome (condition where patient experiences rigidity, decreased consciousness, fever and fluctuating blood pressure and heart rate – may be fatal).
Gastrointestinal- Bowel disturbances, primarily diarrhea and nausea.
Skin- Transient flushing of face or upper body with high IV doses.
Hormone- Galactorrhea ( spontaneous flow of milk from the breast), breast enlargement in men and increase in serum prolactin.
Genitourinary- Absence of a menstrual period, elevation of aldosterone, fluid retention, impotence, incontinence and urinary frequency.
Liver- Liver toxicity (rare).
Blood- Decrease in white blood cells and changes in hemoglobin.
Hypersensitivity- Rapid swelling of dermis, including glossal or laryngeal edema (rare), rash and itching.
Miscellaneous- Visual disturbances.
Other Precautions : 
* Insulin dosage or timing of dosage may require adjustment for diabetes patients.
Storage Conditions : 
Injection: Store it at 25°C. Store it in an airtight container and protect from light.

Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.
Member Comments ( 1 )
Sir I am asking one question metoclopramide hcl is very older drug but a/c to my knowledge there is no dispersible tablet found in the market what the reason behind this `
(Posted by sanjay netam, India Date : 8/18/2008 )

Browse the Drugs alphabetically

Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
Drugs Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z