Methylprednisolone - Drug Information

Generic Name : Methylprednisolone | Pronunciation : meth ill pred niss' oh lone

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Latest prescription information about Methylprednisolone. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y42.0 | Therapeutic Classification : Hormones
Drug Information

Trade Name(s): 

India : 

International : 

Medrol, Medrol Dosepak, MethylPREDNISolone Dose Pack, Medrol, Meprolone

Why it is prescribed (Indications) : 

This medication is a corticosteroid prescribed for severe allergies, arthritis, asthma, certain blood disorders and skin conditions.  It prevents the release of substances in the body that cause inflammation.

When it is not to be taken (Contraindications): 


Pregnancy Category :






Category C :

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 

PO- The recommended dose range is 4 to 32mg/day.
IV- 1gm every 6 8 weeks.

How it should be taken : 

It comes as a tablet to take by mouth, with food.
It also comes as a solution for injection to be administered by a healthcare provider into the vein.

Warnings and Precautions : 

Caution should be exercised in patients with history of heart problems, heart attack, high blood pressure, kidney, liver disease, diabetes, seizures, under active thyroid, adrenal gland problems, mental problems, any allergy, who are taking other medications, infections, stomach problems, muscle weakness, elderly, children, during pregnancy and breastfeeding.
Avoid contact with people who have infections.
It may cause serious increase in blood pressure, salt and water retention, calcium deficiency, take proper diet.
It may affect blood sugar level; monitor sugar level regularly while taking this medication.

Side Effects : 

- Heart failure, high blood pressure and fluid retention.

- Muscle weakness, loss of muscle mass, joint inflammation, tendon rupture, vertebral compression and fractures.

- Peptic ulcer and abdominal distention.

- Facial swelling increased sweating, redness and rash.

   Central Nervous System
- Stroke, convulsions, unsteadiness and headache.

- Suppression of growth in children and menstrual irregularities.

- Increased blood sugar level.

- Increased eye pressure.

Other Precautions : 

Avoid excess dosage.

Storage Conditions : 

Store it at controlled room temperature (20 to 25C).


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At what dosage and duration of use does this cause elevated blood sugar levels and fluid retention?
Anuvathsa  Friday, September 12, 2014
I was having pain on my both the feet. My high blood pressure and Uric acid is controlled with intake of medicine for the past 15 yrs. because of the pain in my both legs below the knee doctor advice following medicine presently for three days and as per adice I carried out blood test. The result of serum crp test is 36.55 mg/liter, Haemoglobin[hb] is 13.9mg/dl, Total Leukoc ount 8900/cumm,Medicine for 3 days Predmet 6/2tab per day;Feldex 2 tab/per day
Swapanpuri  Sunday, March 16, 2014
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