Methimazole - Drug Information

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General Information on Methimazole

Generic Name : Methimazole

Pronunciation : meth im' a zole

Latest prescription information about Methimazole. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y42.2 | Therapeutic Classification : Thyroid and Antithyroid Agents

Trade Names/Brand Names of Methimazole

India- Methimez .
International- Mercazole, Thyrozole.

Why is Methimazole Prescribed? (Indications)

This medication is an antithyroid agent, prescribed for hyperthyroidism. It works by inhibiting the production of thyroid hormone.

When should Methimazole not to be taken? (Contraindications)

Hypersensitivity.

Pregnancy Category

A B C D X

Category D :

There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.

What is the dosage of Methimazole?

Adult: The initial daily dosage is 15 mg. It may be increased upto 60 mg, divided into 3 doses at 8-hour intervals. The maintenance dosage is 5 to 15 mg daily.
Pediatric: Initially, the daily dosage is 0.4 mg/kg, divided into 3 doses and given at 8-hour intervals.

How should Methimazole be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Methimazole?

Caution should be exercised in patients with history of decrease in blood cells, liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.
It may cause drowsiness, dizziness, or lightheadedness, do not drive a car or operate machinery while taking this medication.

What are the side effects of Methimazole?

   Skin : Rash, hives, abnormal loss of hair, itching and skin pigmentation.
   Gastrointestinal : Nausea, vomiting and stomach upset.
   Musculoskeletal : Joint/muscle pain.
   Central Nervous System : Tingling, headache, drowsiness, dizziness and fainting.
   Miscellaneous : Loss of taste, swelling and jaundice.

What are the other precautions for Methimazole?

Avoid excess dosage.

What are the storage conditions of Methimazole?

Store it at controlled room temperature (15 to 30C), and in an airtight container. Keep away from children.

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