Generic Name : Methimazole Pronunciation : meth im' a zole Therapeutic Classification : Thyroid and Antithyroid Agents ICD Code : Y42.2
India- Methimez .
International- Mercazole, Thyrozole. Why it is prescribed (Indications) : This medication is an antithyroid agent, prescribed for hyperthyroidism. It works by inhibiting the production of thyroid hormone. When it is not to be taken (Contraindications): Hypersensitivity.
Dosage & When it is to be taken :
Adult: The initial daily dosage is 15 mg. It may be increased upto 60 mg, divided into 3 doses at 8-hour intervals. The maintenance dosage is 5 to 15 mg daily.
Pediatric: Initially, the daily dosage is 0.4 mg/kg, divided into 3 doses and given at 8-hour intervals. How it should be taken : It comes as a tablet to take by mouth, with or without food. Warnings and Precautions :
* Caution should be exercised in patients with history of decrease in blood cells, liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause drowsiness, dizziness, or lightheadedness, do not drive a car or operate machinery while taking this medication. Side Effects :
Skin - Rash, hives, abnormal loss of hair, itching and skin pigmentation.
Gastrointestinal - Nausea, vomiting and stomach upset.
Musculoskeletal - Joint/muscle pain.
Central Nervous System - Tingling, headache, drowsiness, dizziness and fainting.
Miscellaneous - Loss of taste, swelling and jaundice.
* Avoid excess dosage. Storage Conditions :
Store it at controlled room temperature (15° to 30°C), and in an airtight container. Keep away from children.
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