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Mercaptopurine
Latest prescription information about Mercaptopurine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Mercaptopurine
Pronunciation : mer kap toe pyoor' een
Therapeutic Classification : Chemotherapy
Trade Name(s):
India- 6 Mp Tab, Captomer, Mesna, Empurine Tab, Mercapto Tab, Puri-Nethol Tab, Purinetone Tab. International- Purinethol. When it is not to be taken (Contraindications): Contraindicated in patients who have prior resistance to this drug, and hypersensitivity.
When it is to be taken : Adult: PO- Acute lymphatic Leukemia: Usual maintenance dose: Initial: 1.5-2.5 mg/kg/day, may increase carefully up to 5 mg/kg/day. Crohn's disease Initial: 1-1.5 mg/kg/day. Up to 125 mg/day. How it should be taken : It comes as a tablet to take by mouth, on an empty stomach. Special Instruction : * Caution should be exercised in patients with history of bone marrow problems, anemia, low white blood cell or platelet levels, unusual bruising or bleeding, liver or kidney problems, infections, any allergy, during pregnancy and breastfeeding. * Avoid contact with people who have infections. * It may reduce platelet counts; to prevent bleeding avoid injury or bruising. * Patient may develop with increased risk other than cancer; if any unusual tumor appears consult with your doctor immediately. * Avoid vaccination while taking this medication. * Monitor blood cell counts, liver function tests, and TPMT enzyme activity regularly while taking this medication. Side Effects : Serious Effects - Bone marrow depression and liver damage. Genitourinary - Abnormally elevated blood level of uric acid. Gastrointestinal - Intestinal ulceration, nausea, vomiting, and loss of appetite. Miscellaneous - Hair loss and decrease in sperm count. * Avoid excess dosage. Storage Conditions : Store it at controlled room temperature (15° to 25°C). |
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