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Mefenamic Acid

Latest prescription information about Mefenamic Acid. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Mefenamic Acid
Pronunciation : me fe nam' ik
Trade Name(s): 
India- Abdrot-Plus Tab, Colifine Tab, Dysmen 500 Tab, Dysmen Forte Tab, Flexiwin-Mf Susp, Gefplus Tab, Lenagesic Tab, Mefac Tab, Mefacid Dispertab, Mefacid Forte Tab, Mefacid Susp, Mefacid Tab, Mefdol Forte Tab, Mefegesic Tab, Meflup Forte Tab, Meflup Tab, Mefsine Tab, Meftagesic Susp, Meftagesic Tab, Meftal Forte Tab, Meftal Tab, Meftal-P Dispertab, Meftal-P Susp, Mefzys Drops, Mepar Forte Tab, Mepar Tab, Pal-Mf Tab, Ponstan Susp, Ponstan Tab, Spamic Plus Tab, Spasmonil Forte Tab, Taurpol Mf Tab, Vahspas Tab.
International- Ponstel.
Why it is prescribed (Indications) : This medication is a non-steroidal anti-inflammatory drug (NSAID), prescribed for dysmenorrhea and other pain. It decreases inflammation and uterine contractions.

When it is not to be taken (Contraindications): 

Contraindicated in patients who have experienced asthma, hives, allergic reactions after taking aspirin or other NSAIDs, peri-operative pain, ulcer, kidney disease and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : PO- The recommended dose is 500 mg as an initial dose followed by 250 mg every 6 hours as needed.
How it should be taken : It comes as a tablet and capsule to take by mouth, with or without food.
Special Instruction : 
* Caution should be exercised in patients with history of high blood pressure, blood disorders, bleeding or clotting problems, heart disease, dehydration, alcoholism, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
* Patient may develop with stomach ulcer or bleeding, so avoid long-term use of this medication.
* Avoid taking aspirin with this medication.
* Monitor kidney function, complete blood cell counts, and blood pressure regularly while taking this medication.
Side Effects : 
Gastrointestinal - Abdominal pain, constipation, diarrhea, indigestion, flatulence, gross bleeding/perforation, gastric/peptic ulcers, heartburn, nausea, mouth ulcer, GI ulcers, vomiting, anemia, elevated liver enzymes, and blood vomiting.
Body as a whole - Fever, infection and sepsis.
Heart - Heart failure, high blood pressure, fast heart rate and fainting.
Liver - Liver inflammation and jaundice.
Blood - Eosinophilia, decrease in white blood cells, bruising, blood in stool and rectal bleeding.
Metabolic - Weight changes.
Central Nervous system - Anxiety, weakness, confusion, depression, dream abnormalities, drowsiness, dizziness, sleeplessness, uneasiness, headache, nervousness, tingling and tremors.
Respiratory - Asthma and difficulty in breathing.
Skin - Hair loss, sensitivity to light, itching and increased sweating.
Eye and ENT - Blurred vision and ringing in the ear.
Genitourinary - Bladder inflammation, painful urination, blood in urine and kidney failure.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature (20- 25°C).

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Member Comments ( 1 )
After withdrawn of nimesulide susp. in IPM some padiaticians prefering paracetamol+mefenamic acid susp.as antipyretics , whether it is safe, efficacious in children?
(Posted by msuryanarayan, India Date : 9/1/2011 )

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