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Generic Name : Medroxyprogesterone
Pronunciation : me drox, ee proe jess' te rone
Trade Name(s):
India- Depo Progestin Inj, Depo-Provera Inj, Depro Tab, Deviry Tab, Dubloc Tab, Embryogen Tab, Empeea Tab, Farlutal Tab, Geeva Tab, Maxogest Tab, Medrigest Tab, Medronorm Tab, Medtet Tab, Megest Tab, Meprate Tab, Modus Tab, Orgamed Tab, Premelle Tab, Provera Tab, Regeeva Tab, Regumed Tab, Tab Litmus Tab.
International- Amen, Curretab, Cycrin, Prodroxy, Provera.
Why it is prescribed (Indications) : This medication is a progestin hormone, prescribed for menstrual problems, breast cancer and prevention of pregnancy.
When it is not to be taken (Contraindications): Contraindicated in patients with known or suspected pregnancy, breast cancer, liver disease and hypersensitivity.
Category X : Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
When it is to be taken : PO- The recommended dose is 5 to 20 mg.
IM- 50 – 150mg at 1 – 3 month interval.
How it should be taken : It comes as a tablet to take by mouth, with or without food.
It also comes as a solution for injection to be administered by a healthcare provider into the large muscle.
Special Instruction :
* Caution should be exercised in patients with history of breast cancer, unexplained vaginal bleeding, abortion, blood clot events, stroke, seizures, migraine, headaches, depression, asthma, diabetes, heart, kidney, or liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.
* Avoid exposure to sunlight; otherwise it may cause dark skin patches.
* It may affect blood sugar level; monitor sugar level regularly.
Side Effects :
Body as a Whole -
Headache, abdominal pain/discomfort, fatigue, backache, painful menstruation and hot flashes.
Metabolic -
Increased weight.
Central Nervous System -
Nervousness, dizziness, decreased libdio, paralysis, facial palsy, tingling and drowsiness.
Genitourinary -
Menstrual irregularities, excess bleeding, breast cancer, unexpected pregnancy, vaginal cyst, infections, increased sexual activity and absence of menstrual cycle.
Heart -
Fainting, fast heart rate, deep vein thrombosis, pulmonary embolus and varicose veins.
Gastrointestinal -
Changes in appetite, jaundice, excessive thirst and rectal bleeding.
Blood -
Anemia and blood disorders.
Musculoskeletal -
Joint inflammation.
Respiratory -
Difficulty in breathing and asthma.
Skin -
Excessive sweating, body odor and dry skin.
Other Precautions :
* Avoid excess dosage.
Storage Conditions :
Store it at controlled room temperature (20° to 25°C), and in an airtight container.
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