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Mecamylamine

Latest prescription information about Mecamylamine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Mecamylamine
Pronunciation : mek-ah-MIL-a-meen
Therapeutic Classification : Anti- Hypertensives
ICD Code : Y52.5
Trade Name(s): 
International- Inversine.
Why it is prescribed (Indications) : This medication is an antihypertensive agent, prescribed for high blood pressure. It works by relaxing and dilating (widening) blood vessels.
When it is not to be taken (Contraindications): Contraindicated in patients with heart diseases or recent heart attack, excessive amount of urea in blood and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : Initial: The recommended dose is one 2.5 mg tablet twice a day. It may be increased if needed.
How it should be taken : It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of increased eye pressure, stomach problem, heart disease, poor blood circulation, stroke, kidney disease, urination problems, enlarged prostate, salt-restricted diet, elderly, children, during pregnancy and breastfeeding.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
Side Effects : 
Gastrointestinal- Obstruction of the intestine, constipation, vomiting, nausea, loss of appetite, inflammation of tongue and dryness of mouth.
Heart- Fainting and low blood pressure.
Central Nervous System- Dizziness, epilepsy, jerking, mental aberrations, tremor and tingling.
Respiratory- Lung swelling and fibrosis.
Genitourinary- Urinary retention, impotence and decreased libido.
Eye- Blurred vision and dilated pupils.
Miscellaneous- Weakness, fatigue and sedation.
Other Precautions : 
* Avoid alcohol consumption.
* Patient may develop with increased risk of diarrhea, if it so stop the medication.
Storage Conditions : 
Store it at room temperature (25°C) and in an airtight container.


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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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