Maprotiline - Drug Information

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General Information on Maprotiline

Generic Name : Maprotiline

Pronunciation : ma proe' ti leen

Latest prescription information about Maprotiline. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y49.0 | Therapeutic Classification : Psychotherapeutics

Trade Names/Brand Names of Maprotiline

International- Deprilept, ludiomil, Psymion.

Why is Maprotiline Prescribed? (Indications)

This medication is an antidepressant, prescribed for depression and anxiety.  It works by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance.

When should Maprotiline not to be taken? (Contraindications)

Contraindicated in patients with increased eye pressure, urinary retention, convulsive disorder, heart attack, co-administration with MAO inhibitor or within 14 days of treatment with MAOIs, children and hypersensitivity.

Pregnancy Category

A B C D X

Category B :

Animal studies have failed to demonstrate a risk to the fetus and appropriate studies on pregnant women are lacking.

What is the dosage of Maprotiline?

Adults: The recommended initial dose is 75 mg daily in 2 or 3 divided doses.

How should Maprotiline be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Maprotiline?

Caution should be exercised in patients with history of increased eye pressure, enlarged prostate, difficulty in urinating, seizures, brain tumor, head injury, overactive thyroid, liver, kidney or heart disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.
It may cause dizziness or drowsiness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
Avoid alcohol consumption.
It may increase suicidal tendency in children and teenagers, if so consult with your doctor.
Avoid becoming overheated, otherwise it may cause heatstroke.
Patient may develop with involuntary movements; inform your doctor immediately if it so.

What are the side effects of Maprotiline?

   Most Common : Dry mouth, daytime sleeping, vertigo, blurred vision, constipation, headache and nervousness.
   Central Nervous System : Dizziness, lightheadedness, fatigue and drowsiness.
   Gastrointestinal : Nausea, vomiting and constipation.
   Heart : Irregular heart rate.
   Genitourinary : Difficulty in urination, frequent urination and changes in sex drive.
   Miscellaneous : Fever, chills, sore throat, flu-like symptoms, blurred vision, difficulty in breathing and excessive sweating.

What are the other precautions for Maprotiline?

Avoid exposure to sunlight; otherwise it may cause sunburn easily.
Avoid excess dosage.

What are the storage conditions of Maprotiline?

Store it at room temperature, and in an airtight container. Keep away from children.

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