Contraindicated in patients who are taking carbamazepine, clarithromycin, efavirenz, certain HIV protease inhibitors, itraconazole, ketoconazole, nefazodone, nevirapine, phenobarbital, primidone, St. John's wort, telithromycin, or voriconazole, and known hypersensitivity.

Pregnancy Category :

A B C D X

Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.