Trade Names/Brand Names :
Why it is prescribed :
This medication is a chloride channel activator, prescribed for chronic constipation and irritable bowel syndrome. It increases the amount of fluid that flows into the bowel and allowing the stool to pass more easily.
When it is not to be taken (Contraindications):
Contraindicated in patients with gastrointestinal obstruction, and hypersensitivity.
Category C :
Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.
Dosage & When it is to be taken (Indications):
The recommended dose is 24 mcg twice daily orally with food and water.
How it should be taken :
It comes as a capsule, to take by mouth, with food.
Warnings and Precautions :
• Caution should be exercised in patients with history of diarrhea, stomach or bowel blockage, who are taking other medications, any allergy, children, during pregnancy and breastfeeding.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.
Side Effects :
Nausea, diarrhea, abdominal pain, abdominal distension, flatulence, vomiting, loose stools, abdominal discomfort, indigestion, dry mouth and stomach discomfort.
• Central Nervous system
Headache, and dizziness.
Swelling in the extremities, fatigue and chest discomfort/pain.
Other Precautions :
Avoid excess dosage.
Storage Conditions :
Store it at controlled room temperature (15° to 30°C).