Loxapine - Drug Information

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General Information on Loxapine

Generic Name : Loxapine

Pronunciation : lox' a peen

Latest prescription information about Loxapine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y49.5 | Therapeutic Classification : Psychotherapeutics

Why is Loxapine Prescribed? (Indications)

This medication is a tranquilizer, prescribed for emotional and mental conditions.  It works by decreasing abnormal excitement in the brain.

When should Loxapine not to be taken? (Contraindications)

Contraindicated in patients with coma, severe central nervous system depression, and hypersensitivity.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Loxapine?

PO- The recommended dose range is 10 250 mg/day in divided doses.

How should Loxapine be taken?

It comes as a capsule and liquid to take by mouth, with food.

What are the warnings and precautions for Loxapine?

Caution should be exercised in patients with history of seizures, difficulty in urinating, increased eye pressure, breast cancer, brain tumor, heart disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.
It may cause dizziness or drowsiness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
Avoid alcohol consumption.
Do not become overheated; otherwise it may cause heat stroke.
Patient may develop with increased risk of Neuroleptic Malignant Syndrome (NMS) with the following symptoms: increased body heat, muscle rigidity, altered mental abilities. If it so consult with your doctor.

What are the side effects of Loxapine?

   Central Nervous System : Dizziness, faintness, staggering gait, muscle twitching, weakness, sleeplessness, agitation, tension, seizures, slurred speech, numbness and confusion.
   Heart : Fast heart rate, low/high blood pressure, lightheadedness and fainting.
   Blood : Decrease in white blood cells and platelets.
   Skin : Skin inflammation, swelling, itching, rash, hair loss and scaling.
   Anticholinergic : Dry mouth, nose congestion, constipation, blurred vision, urinary retention and intestinal obstruction.
   Gastrointestinal : Nausea, jaundice and/liver inflammation.
   Others : Weight gain, weight loss, difficulty in breathing, fever, flushing, headache, tingling, increased thirst, absence of menstrual period, breast enlargement in male and menstrual irregularity.

What are the other precautions for Loxapine?

Some patients may develop with involuntary movements; if it so consult with your doctor.
Avoid excess dosage.

What are the storage conditions of Loxapine?

Store it at controlled room temperature (15-30C).


Schedule : H

Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.

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