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Lovastatin

Updated on : April - 2012
Latest prescription information about Lovastatin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Lovastatin
Pronunciation : loe' va sta tin
Therapeutic Classification : Antilipemics
ICD Code : Y52.6
Trade Name(s): 
India- Aztatin Tab, Elstatin Tab, Elstin Tab, Favolip Tab, Lestric Tab, Lipistat Tab, Lochol Tab, Lostatin Tab, Lotin Tab, Lova Tab, Lovacard Tab, Lovadac Tab, Lovalip Tab, Lovameg Tab, Lovastat Tab, Lovastrol Tab, Lovatin Tab, Lovex Tab, Pro Hdl Tab, Recol Tab, Rovacor Tab.
International- Altocor, Altoprev, Mevacor.
Why it is prescribed (Indications) : This medication is a HMG-CoA reductase inhibitor, prescribed for high cholesterol.  It reduces the production of certain fatty substances in the body.
When it is not to be taken (Contraindications):  Contraindicated in patients with liver disease, elevated liver enzymes level, pregnancy, lactation and hypersensitivity.
It should not be co-administered with strong CYP3A4 inhibitors.

Pregnancy Category :

A B C D X
Category X : Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Dosage & When it is to be taken : PO- The recommended dose range is 10-80 mg daily at bedtime.
How it should be taken : It comes as a tablet to take by mouth, with food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of liver disease, alcoholism, who had an organ transplant or surgery, any allergy, who are taking other medications, elderly and children.
* It may cause dizziness or blurred vision, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* Monitor blood cholesterol level, liver function tests and creatine phosphokinase (CPK) blood levels regularly while taking this medication.
Side Effects : 
Body As a Whole - Weakness.
Gastrointestinal - Abdominal pain, non- fatal liver failure, constipation, diarrhea, indigestion, flatulence and nausea.
Musculoskeletal - Muscle cramps, muscle pain, Immune-Mediated Necrotizing Myopathy (IMNM).
Central Nervous System - Dizziness, cognitive impairment (e.g., memory loss, forgetfulness, amnesia, memory impairment, confusion) and headache.
Skin - Rash.
Special Senses - Blurred vision.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature (20-25°C). Store this medication away from light and out the reach of children.
♦ Safety Labeling Changes Approved By FDA

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Member Comments ( 1 )
My doctor says this medicine can cause sleep disorders & insonmia. Asked me to stop .
(Posted by Gary Tan, Malaysia Date : 2/21/2007 )

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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